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Substance Name: Isonixin [INN]
RN: 57021-61-1
UNII: BYX6E7M5QE
InChIKey: WJDDCFNFNAHLAF-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H14-N2-O2

Molecular Weight

  • 242.2766
 
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Names and Synonyms

Name of Substance

  • Isonixin
  • Isonixin [INN]

Synonyms

  • 1,2-Dihydroxy-2-oxo-N-(2,6-xylyl)-3-pyridinecarboxamide
  • 2,6-Xylidid der 2-pyridon-3-carboxylsaure
  • 2,6-Xylidid der 2-pyridon-3-carboxylsaure [German]
  • 2,6-Xylidide of 2-pyridone-3-carboxylic acid
  • 2-Hydroxy-2',6'-nicotinoxylidide
  • EINECS 260-521-6
  • Isonixin
  • Isonixina
  • Isonixina [INN-Spanish]
  • Isonixine
  • Isonixine [INN-French]
  • Isonixinum
  • Isonixinum [INN-Latin]
  • Nixyn
  • Nixyn hermes
  • UNII-BYX6E7M5QE

Systematic Names

  • 2-Hydroxy-2',6'-nicotinoxylidide
  • 3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-(2,6-xylyl)-
  • 3-Pyridinecarboxamide, N-(2,6-dimethylphenyl)-1,2-dihydro-2-oxo- (9CI)
  • Isonixin
  • N-(2,6-Dimethylphenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxamide

Registry Numbers

CAS Registry Number

  • 57021-61-1

FDA UNII

  • BYX6E7M5QE

System Generated Number

  • 0057021611

Structure Descriptors

InChI

1S/C14H14N2O2/c1-9-5-3-6-10(2)12(9)16-14(18)11-7-4-8-15-13(11)17/h3-8H,1-2H3,(H,15,17)(H,16,18)

InChIKey

WJDDCFNFNAHLAF-UHFFFAOYSA-N

Smiles

Cc1cccc(c1NC(=O)c2ccc[nH]c2=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1457, 1977.
mouse LD50 oral 7gm/kg (7000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1457, 1977.
rat LD50 intraperitoneal > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1457, 1977.
rat LD50 oral > 6gm/kg (6000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1457, 1977.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 266.5 deg C   EXP
log P (octanol-water) 1.010 (none)   EST
Atmospheric OH Rate Constant 8.38E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.