Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Paxilline
RN: 57186-25-1
UNII: 3T9U9Z96L7
InChIKey: ACNHBCIZLNNLRS-UBGQALKQSA-N

Classification Codes

  • Cardiovascular Agents
  • Membrane Transport Modulators
  • Natural Product
  • Potassium Channel Blockers

Molecular Formula

  • C27-H33-N-O4

Molecular Weight

  • 435.561
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Paxilline

Synonyms

  • BRN 5317894
  • NSC 658707
  • Paxilline
  • UNII-3T9U9Z96L7

Systematic Names

  • 2H-1-Benzopyrano(5',6':6,7)indeno(1,2-b)indol-3(4bh)-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-, (2-alpha,4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta)-
  • 2H-Pyrano(2'',3'':5',6')benz(1',2':6,7)indeno(1,2-b)indol-3(4bH)-one, 5,6,6a,7,12,12b,12c,13,14,14a-decahydro-4b-hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-, (2R,4bS,6aS,12bS,12cR,14aS)-

Registry Numbers

CAS Registry Number

  • 57186-25-1

FDA UNII

  • 3T9U9Z96L7

System Generated Number

  • 0057186251

Structure Descriptors

InChI

1S/C27H33NO4/c1-24(2,30)23-20(29)14-18-21(32-23)10-11-25(3)26(4)15(9-12-27(18,25)31)13-17-16-7-5-6-8-19(16)28-22(17)26/h5-8,14-15,21,23,28,30-31H,9-13H2,1-4H3/t15-,21-,23-,25+,26+,27+/m0/s1

InChIKey

ACNHBCIZLNNLRS-UBGQALKQSA-N

Smiles

c1ccc2c3c([nH]c2c1)[C@@]1([C@H](C3)CC[C@@]2(C=3[C@H](CC[C@@]12C)O[C@@H](C(C3)=O)C(C)(O)C)O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD oral > 100mg/kg (100mg/kg) BEHAVIORAL: TREMOR Journal of Antibiotics. Vol. 41, Pg. 1868, 1988.
mouse LD oral > 227mg/kg (227mg/kg) BEHAVIORAL: TREMOR Journal of Antibiotics. Vol. 41, Pg. 1868, 1988.
mouse LD50 unreported 150mg/kg (150mg/kg)   "Toxicology, Biochemistry and Pathology of Mycotoxins," Uraguchi, K. and M. Yamazaki, eds., New York, John Wiley & Sons, Inc., 1978Vol. -, Pg. 108, 1978.