Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Indacrinone [USAN:INN]
RN: 57296-63-6
InChIKey: PRKWVSHZYDOZLP-UHFFFAOYSA-N

Note

  • Polyvalent saluretic.

Molecular Formula

  • C18-H14-Cl2-O4

Molecular Weight

  • 365.211
 

Classification Codes

  • Antihypertensive
  • Antirheumatic Agents
  • Diuretic
  • Diuretics
  • Gout Suppressants
  • Natriuretic Agents
  • Renal Agents
  • Reproductive Effect
  • Uricosuric Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Indacrinone [USAN:INN]

Synonyms

  • (+-)-((6,7-Dichloro-2-methyl-1-oxo-2-phenyl-5-indanyl)oxy)acetic acid
  • Acetic acid, ((6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy)-, (+-)-
  • Acide indacrinique
  • Acide indacrinique [INN-French]
  • Acido indacrinico
  • Acido indacrinico [INN-Spanish]
  • Acidum indacrinicum
  • Acidum indacrinicum [INN-Latin]
  • Indacrinona
  • Indacrinona [INN-Spanish]
  • Indacrinona [Spanish]
  • Indacrinone
  • Indacrinonum
  • Indacrinonum [INN-Latin]
  • Indacrinonum [Latin]
  • MK 196
  • MK-196

Systematic Names

  • Acetic acid, ((2,3-dihydro-6,7-dichloro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy)-, (+-)-
  • Acetic acid, ((6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy)-, (+-)-

Registry Numbers

CAS Registry Number

  • 57296-63-6

System Generated Number

  • 0057296636

Structure Descriptors

InChI

1S/C18H14Cl2O4/c1-18(11-5-3-2-4-6-11)8-10-7-12(24-9-13(21)22)15(19)16(20)14(10)17(18)23/h2-7H,8-9H2,1H3,(H,21,22)

InChIKey

PRKWVSHZYDOZLP-UHFFFAOYSA-N

Smiles

c12c(C[C@@](C1=O)(c1ccccc1)C)cc(OCC(O)=O)c(c2Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 246mg/kg (246mg/kg) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED Drugs of the Future. Vol. 13, Pg. 257, 1988.
mouse LD50 oral 592mg/kg (592mg/kg) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED Drugs of the Future. Vol. 13, Pg. 257, 1988.