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Substance Name: Congo red [USP]
RN: 573-58-0
UNII: 3U05FHG59S
InChIKey: IQFVPQOLBLOTPF-HKXUKFGYSA-L
Note
- An acid dye used in testing for hydrochloric acid in gastric contents. It is also used histologically to test for AMYLOIDOSIS.
Molecular Formula
- C32-H24-N6-O6-S2.2Na
Molecular Weight
- 696.674
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- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Coloring Agents
- Drug / Therapeutic Agent
- Human Data
- Mutation Data
- Reproductive Effect
- Skin / Eye Irritant
- TSCA Flag S (Substance is Identified in a Final Significant New Use Rule)
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Names and Synonyms
Name of Substance
- C.I. Direct Red 28
- Congo red
- Congo red [USP]
MeSH Heading
- Congo red
Synonyms
- 1-Naphthalenesulfonic acid, 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-amino-, disodium salt
- AI3-63036
- Atlantic Congo Red
- Atul Congo Red
- Azocard Red Congo
- Benzo Congo Red
- Brasilamina congo 4B
- C.I. 22120
- C.I. Direct Red 28
- C.I. Direct Red 28, disodium salt
- CCRIS 2277
- Cerven kongo
- Cerven kongo [Czech]
- Cerven prima 28
- Cerven prima 28 [Czech]
- Congazone sodium
- Congo red
- Congo Red 4B
- Congo Red 4BX
- Congo Red CR
- Congo Red H
- Congo Red ICI
- Congo Red L
- Congo Red M
- Congo Red N
- Congo Red R
- Congo Red W
- Congo Red WS
- Cotton Red 4BC
- Cotton Red 5B
- Cotton Red L
- Diacotton Congo Red
- Direct Red 28
- Direct Red C
- Direct Red DC-CF
- Direct Red K
- EINECS 209-358-4
- Erie Congo 4B
- Haemomedical
- Haemonorm
- Hemorrhagyl
- Hispamin congo 4B
- HSDB 4225
- Kayaku Congo Red
- Kongorot
- Kongorot [German]
- Mitsui Congo Red
- Natrium-salz der diphenyl-bis-azo-bis-naphthylamin-4-sulfonsaeure
- Natrium-salz der diphenyl-bis-azo-bis-naphthylamin-4-sulfonsaeure [German]
- NSC 56651
- NSC 7232
- Peeramine Congo Red
- Red K
- Sodium diphenyldiazo-bis(alpha-naphthylaminesulfonate)
- Solucongo
- Sugai Congo Red
- Tertrodirect Red C
- Trisulfon Congo Red
- UNII-3U05FHG59S
- Vondacel Red CL
Systematic Names
- 1-Naphthalenesulfonic acid, 3,3'-((1,1'-biphenyl)-4,4'-diylbis(2,1-diazenediyl))bis(4-amino-, sodium salt (1:2)
- 1-Naphthalenesulfonic acid, 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-amino-, disodium salt
- 1-Naphthalenesulfonic acid, 3,3'-(4,4'-biphenylenebis(azo))bis(4-amino-, disodium salt
- C.I. Direct Red 28
- C.I. Direct Red 28, disodium salt (8CI)
- Disodium 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-aminonaphthalene-1-sulphonate)
Registry Numbers
CAS Registry Number
- 573-58-0
FDA UNII
- 3U05FHG59S
Other Registry Numbers
- 1000818-40-5
- 550-08-3
- 70248-72-5
- 87440-95-7
System Generated Number
- 0000573580
Molecular Formulas
Molecular Formula
- C32-H24-N6-O6-S2.2Na
Molecular Formula Fragments
- C32-H24-N6-O6-S2
- COMPONENT
- Na
Structure Descriptors
InChI
InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;InChIKey
IQFVPQOLBLOTPF-HKXUKFGYSA-LSmiles
[Na+].[Na+].Nc1c(cc(c2ccccc12)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 100mg/kg (100mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BLOOD: CHANGE IN CLOTTING FACTORS | American Journal of the Medical Sciences. Vol. 198, Pg. 73, 1939. |
man | LDLo | intravenous | 1429ug/kg (1.429mg/kg) | BLOOD: CHANGE IN CLOTTING FACTORS LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Deutsche Medizinische Wochenschrift. Vol. 89, Pg. 1845, 1964. |
man | LDLo | oral | 143mg/kg (143mg/kg) | VASCULAR: OTHER CHANGES | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 185, 1969. |
mouse | LDLo | intravenous | 250mg/kg (250mg/kg) | Journal of Immunology. Vol. 68, Pg. 53, 1952. | |
pigeon | LDLo | intravenous | 120mg/kg (120mg/kg) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: CHANGE IN CLOTTING FACTORS | American Journal of the Medical Sciences. Vol. 198, Pg. 73, 1939. |
rabbit | LDLo | intravenous | 230mg/kg (230mg/kg) | BLOOD: CHANGE IN CLOTTING FACTORS LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of the Medical Sciences. Vol. 198, Pg. 73, 1939. |
rabbit | LDLo | oral | 6gm/kg (6000mg/kg) | Office of Toxic Substances Report. Vol. OTS, | |
rabbit | LDLo | skin | 4gm/kg (4000mg/kg) | Office of Toxic Substances Report. Vol. OTS, | |
rat | LCLo | inhalation | 50gm/m3/1H (50000mg/m3) | Office of Toxic Substances Report. Vol. OTS, | |
rat | LD50 | oral | 15200mg/kg (15200mg/kg) | Office of Toxic Substances Report. Vol. OTS, | |
rat | LDLo | intravenous | 160mg/kg (160mg/kg) | BLOOD: CHANGE IN CLOTTING FACTORS LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of the Medical Sciences. Vol. 198, Pg. 73, 1939. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | >360 | deg C | EXP | |
log P (octanol-water) | 2.630 | (none) | EST | |
Water Solubility | 1.16E+05 | mg/L | 25 | EXP |
Vapor Pressure | 2.24E-30 | mm Hg | 25 | EST |
Atmospheric OH Rate Constant | 2.33E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.