Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Etoperidone hydrochloride [USAN]
RN: 57775-22-1
UNII: 2FSU2FR80J
InChIKey: BHKPQZVLIZKSAG-UHFFFAOYSA-N

Classification Codes

  • Antidepressant
  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C19-H28-Cl-N5-O.Cl-H

Molecular Weight

  • 414.378
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Etoperidone hydrochloride
  • Etoperidone hydrochloride [USAN]

Synonyms

  • 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3,4-diethyl-delta(sup 2)-1,2,4-triazolin-5-one monohydrochloride
  • 3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-4,5-diethyl-2,4-dihydro-, monohydrochloride
  • AF-1191
  • Axiomin
  • Clopradone, trazolinone
  • Depracer
  • EINECS 260-942-5
  • Etonin
  • Etoperidone HCl
  • Etoperidone hydrochloride
  • Etoran
  • McN-A 2673-11
  • McN-A-2673-11
  • NSC 304398
  • ST-1191
  • Staff
  • Tropene
  • UNII-2FSU2FR80J

Systematic Names

  • 2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one monohydrochloride
  • 3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-4,5-diethyl-2,4-dihydro-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 57775-22-1

FDA UNII

  • 2FSU2FR80J

Other Registry Number

  • 64609-60-5

Related Registry Number

  • 52942-31-1 (Parent)

System Generated Number

  • 0057775221

Molecular Formulas

Molecular Formula

  • C19-H28-Cl-N5-O.Cl-H

Molecular Formula Fragments

  • C19-H28-Cl-N5-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H28ClN5O.ClH/c1-3-18-21-25(19(26)24(18)4-2)10-6-9-22-11-13-23(14-12-22)17-8-5-7-16(20)15-17;/h5,7-8,15H,3-4,6,9-14H2,1-2H3;1H

InChIKey

BHKPQZVLIZKSAG-UHFFFAOYSA-N

Smiles

c1ccc(cc1N1CCN(CCCn2c(n(CC)c(n2)CC)=O)CC1)Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 135mg/kg (135mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978.
mouse LD50 intravenous 68mg/kg (68mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979.
mouse LD50 oral 518mg/kg (518mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979.
rat LD50 intraperitoneal 120mg/kg (120mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978.
rat LD50 intravenous 62mg/kg (62mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 417, 1978.
rat LD50 oral 397mg/kg (397mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979.
rat LD50 subcutaneous 543mg/kg (543mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 294, 1979.