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Substance Name: 8-Aminoquinoline
RN: 578-66-5
UNII: U34EAV21TG
InChIKey: WREVVZMUNPAPOV-UHFFFAOYSA-N

Note

  • Antimalarial; sitamaquine (WR-6026) is an orally active 8-aminoquinoline analog.

Molecular Formula

  • C9-H8-N2

Molecular Weight

  • 144.176
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • 8-Aminoquinoline

Synonyms

  • 5-22-10-00316 (Beilstein Handbook Reference)
  • 8-Aminoquinoline
  • 8-Quinolylamine
  • BRN 0114474
  • CCRIS 1683
  • EINECS 209-427-9
  • NC 066
  • NSC 7933
  • UNII-U34EAV21TG
  • WR 6920

Systematic Names

  • 8-Aminoquinoline
  • 8-Quinolinamine
  • 8-Quinolylamine
  • Quinoline, 8-amino-

Registry Numbers

CAS Registry Number

  • 578-66-5

FDA UNII

  • U34EAV21TG

Other Registry Number

  • 1412898-64-6

Related Registry Number

  • 5330-29-0 (di-HCl)

System Generated Number

  • 0000578665

Structure Descriptors

InChI

InChI=1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2

InChIKey

WREVVZMUNPAPOV-UHFFFAOYSA-N

Smiles

Nc1cccc2cccnc12

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 70 deg C   EXP
pKa Dissociation Constant 3.95 (none) 20 EXP
log P (octanol-water) 1.79 (none)   EXP
Water Solubility 8220 mg/L 25 EST
Vapor Pressure 5.50E-04 mm Hg 25 EST
Henry's Law Constant 2.43E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.00E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.