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Substance Name: Testosterone [USP:INN:BAN]
RN: 58-22-0
UNII: 3XMK78S47O
InChIKey: MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Note

  • A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

Molecular Formula

  • C19-H28-O2

Molecular Weight

  • 288.4282
 

Classification Codes

Classification Codes

  • Androgen
  • Androgens
  • Drug / Therapeutic Agent
  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • DEA Schedule III
  • Overall Carcinogenic Evaluation: Group 2A

Names and Synonyms

Name of Substance

  • Testosterone
  • Testosterone [USP:INN:BAN]

MeSH Heading

  • Testosterone

Synonyms

  • 17-beta-Hydroxy-delta(sup 4)-androsten-3-one
  • 17-beta-Hydroxyandrost-4-en-3-one
  • 17-Hydroxy-(17-beta)-androst-4-en-3-one
  • 17-Hydroxy-(17beta)-androst-4-en-3-one
  • 17beta-Hydroxy-delta(sup4)-androsten-3-one
  • 17beta-Hydroxyandrost-4-en-3-one
  • 17beta-Hydroxyandrost-4-ene-3-one
  • 7-beta-Hydroxyandrost-4-en-3-one
  • AA 2500
  • Andro 100
  • Androderm
  • AndroGel
  • Androgel 1%
  • Androgel 1.62%
  • Androlin
  • Andronaq
  • Andropatch
  • Androst-4-en-17beta-ol-3-one
  • Androst-4-en-3-one, 17-beta-hydroxy-
  • Androst-4-en-3-one, 17-hydroxy-, (17-beta)-
  • Androst-4-en-3-one, 17beta-hydroxy-
  • Andrusol
  • Axiron
  • Bio-T-Gel
  • CCRIS 574
  • CDB 111C
  • COL 1621
  • CompleoTRT
  • CP 601B
  • Cristerona T
  • Cristerone T
  • delta(sup 4)-Androsten-17(beta)-ol-3-one
  • delta4-Androsten-17beta-ol-3-one
  • EC 200-370-5
  • EINECS 200-370-5
  • Fortesta
  • Geno-cristaux gremy
  • Homosteron
  • Homosterone
  • HSDB 3398
  • Intrinsa
  • LibiGel
  • LPCN 1021
  • Malerone
  • Malestrone (amps)
  • Malogen, aquaspension injection
  • Mertestate
  • Nasobol
  • Natesto
  • Neo-Hombreol F
  • Neo-testis
  • Neotestis
  • NSC 9700
  • Oreton
  • Oreton-F
  • Orquisteron
  • Perandren
  • Percutacrine androgenique
  • Primotest
  • Primoteston
  • Relibra
  • Striant
  • Sustanon
  • Sustanone
  • Sustason 250
  • Synandrol F
  • Tefina
  • Teslen
  • Testandrone
  • Testex
  • Testiculosterone
  • Testim
  • Testobase
  • Testoderm
  • Testoderm TTS
  • Testogel
  • Testoject-50
  • Testopropon
  • Testosteroid
  • Testosteron
  • Testosterona
  • Testosterona [INN-Spanish]
  • Testosterone
  • Testosterone hydrate
  • Testosteronum
  • Testosteronum [INN-Latin]
  • Testostosterone
  • Testoviron
  • Testoviron schering
  • Testoviron T
  • Testrone
  • Testryl
  • Tlando
  • trans-Testosterone
  • UNII-3XMK78S47O
  • Virormone
  • Virosterone
  • Vogelxo

Systematic Names

  • Androst-4-en-3-one, 17-hydroxy-, (17beta)-
  • Testosterone

Superlist Names

  • Androst-4-en-3-one, 17-hydroxy-, (17beta)-
  • DEA No. 4000
  • Testosterone
  • Testosterone and its esters
  • Testosterone [Androgenic steroids, anabolic]

Registry Numbers

CAS Registry Number

  • 58-22-0

FDA UNII

  • 3XMK78S47O

Other Registry Number

  • 1050678-68-6

System Generated Number

  • 0000058220

Structure Descriptors

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChIKey

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Smiles

[C@@H]12[C@@H]([C@@]3(C(=CC(=O)CC3)CC2)C)CC[C@]2([C@H]1CC[C@@H]2O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 oral > 5gm/kg (5000mg/kg)   Toksikologicheskii Vestnik. Vol. (2), Pg. 6, 1996.
rat LDLo intraperitoneal 326mg/kg (326mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 116, 1941.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 155 deg C   EXP
log P (octanol-water) 3.32 (none)   EXP
Water Solubility 23.4 mg/L 25 EXP
Vapor Pressure 2.23E-08 mm Hg 25 EST
Henry's Law Constant 3.53E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.07E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.