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Substance Name: Inosine [INN:JAN]
RN: 58-63-9
UNII: 5A614L51CT
InChIKey: UGQMRVRMYYASKQ-KQYNXXCUSA-N
Note
- A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed).
Molecular Formula
- C10-H12-N4-O5
Molecular Weight
- 268.2278
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antiviral (COVID-19)
- Drug / Therapeutic Agent
- Mutation Data
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Names and Synonyms
Name of Substance
- Inosine
- Inosine [INN:JAN]
MeSH Heading
- Inosine
Synonyms
- 9-beta-D-Ribofuranosylhypoxanthine
- AI3-52241
- Atorel
- beta-D-Ribofuranoside, hypoxanthine-9
- beta-Inosine
- EINECS 200-390-4
- HXR
- Hypoxanthine D-riboside
- Hypoxanthine nucleoside
- Hypoxanthine ribonucleoside
- Hypoxanthine riboside
- Hypoxanthine, 9-beta-D-ribofuranosyl-
- Hypoxanthosine
- INO
- INO 495
- Inosina
- Inosina [INN-Spanish]
- Inosine
- Inosinum
- Inosinum [INN-Latin]
- NSC 20262
- Oxiamin
- Panholic-L
- Pantholic-L
- Ribonosine
- Selfer
- Trophicardyl
- UNII-5A614L51CT
Systematic Name
- Inosine
Registry Numbers
CAS Registry Number
- 58-63-9
FDA UNII
- 5A614L51CT
Other Registry Numbers
- 12712-98-0
- 132953-54-9
- 28861-88-3
- 292853-81-7
- 4181-51-5
- 691344-25-9
- 740029-83-8
System Generated Number
- 0000058639
Structure Descriptors
InChI
InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1InChIKey
UGQMRVRMYYASKQ-KQYNXXCUSA-NSmiles
OC[C@H]1O[C@H]([C@H](O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 3175mg/kg (3175mg/kg) | Pharmaceutical Chemistry Journal Vol. 20, Pg. 160, 1986. | |
mouse | LD50 | intravenous | > 2800mg/kg (2800mg/kg) | Drugs in Japan Vol. -, Pg. 156, 1995. | |
mouse | LD50 | oral | > 20gm/kg (20000mg/kg) | Drugs in Japan Vol. 6, Pg. 77, 1982. | |
mouse | LD50 | subcutaneous | 5gm/kg (5000mg/kg) | Drugs in Japan Vol. 6, Pg. 77, 1982. | |
rat | LD50 | intraperitoneal | 2900mg/kg (2900mg/kg) | Drugs in Japan Vol. 6, Pg. 77, 1982. | |
rat | LD50 | intravenous | > 2gm/kg (2000mg/kg) | Drugs in Japan Vol. 6, Pg. 77, 1982. | |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Drugs in Japan Vol. -, Pg. 156, 1995. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 218 dec | deg C | EXP | |
log P (octanol-water) | -2.10E+00 | (none) | EXP | |
Water Solubility | 1.58E+04 | mg/L | 20 | EXP |
Vapor Pressure | 1.40E-14 | mm Hg | 25 | EST |
Henry's Law Constant | 3.28E-23 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 8.78E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.