Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Idebenone [INN:JAN]
RN: 58186-27-9
UNII: HB6PN45W4J
InChIKey: JGPMMRGNQUBGND-UHFFFAOYSA-N

Classification Codes

  • Antioxidants
  • Drug / Therapeutic Agent
  • Protective Agents

Molecular Formula

  • C19-H30-O5

Molecular Weight

  • 338.441
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Idebenone
  • Idebenone [INN:JAN]

Synonyms

  • 6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
  • BRN 2001459
  • CV 2619
  • Idebenona
  • Idebenona [Spanish]
  • Idebenone
  • Idebenonum
  • Idebenonum [Latin]
  • UNII-HB6PN45W4J

Systematic Names

  • 2,5-Cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
  • 2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-
  • 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone

Registry Numbers

CAS Registry Number

  • 58186-27-9

FDA UNII

  • HB6PN45W4J

System Generated Number

  • 0058186279

Structure Descriptors

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChIKey

JGPMMRGNQUBGND-UHFFFAOYSA-N

Smiles

C1(=C(C(C(C)=C(C1=O)CCCCCCCCCCO)=O)OC)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported > 1gm/kg (1000mg/kg)   Chemical and Pharmaceutical Bulletin. Vol. 39, Pg. 367, 1991.
mouse LD50 intraperitoneal 757mg/kg (757mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.
mouse LD50 subcutaneous > 10gm/kg (10000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.
rat LD50 intraperitoneal 830mg/kg (830mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.
rat LD50 oral 10gm/kg (10000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985.