Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Carboprost tromethamine [USAN:USP]
RN: 58551-69-2
UNII: U4526F86FJ
InChIKey: UMMADZJLZAPZAW-XOWPVRJPSA-N

Notes

  • A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of PREGNANCY.
  • Drug combination consisting of these cpds.

Molecular Formula

  • C21-H36-O5.C4-H11-N-O3

Molecular Weight

  • 489.6453
 

Classification Codes

  • Hormone
  • Human Data
  • Oxytocic
  • Oxytocics
  • Reproductive Control Agents
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Carboprost tromethamine
  • Carboprost tromethamine [USAN:USP]

Synonyms

  • (15S)-15-Methylprostaglandin F(sub 2alpha) tromethamine
  • (15S)-15-Methylprostaglandin F2alpha tromethamine
  • (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl)-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • 15(S)15-Methyl pgf2-alpha tromethamine salt
  • 15(S)15-Methyl prostaglandin F2-alpha tromethamine
  • Carboprost trometanol
  • Carboprost tromethamine
  • Hemabate
  • Prostin / 15M
  • U 32921E
  • U-32,921E
  • UNII-U4526F86FJ

Systematic Name

  • Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9-alpha,11-alpha,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

Registry Numbers

CAS Registry Number

  • 58551-69-2

FDA UNII

  • U4526F86FJ

System Generated Number

  • 0058551692

Molecular Formulas

Molecular Formula

  • C21-H36-O5.C4-H11-N-O3

Molecular Formula Fragments

  • C21-H36-O5
  • C4-H11-N-O3
  • COMPONENT

Structure Descriptors

InChI

1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5-,14-12+;/t16-,17-,18+,19-,21+;/m1./s1

InChIKey

UMMADZJLZAPZAW-XOWPVRJPSA-N

Smiles

CCCCC[C@](C)(O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)O.NC(CO)(CO)CO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
infant TDLo intramuscular 73529ng/kg (0.073529mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 865, 1999.
mouse LD50 intravenous 131mg/kg (131mg/kg)   Advances in Prostaglandin and Thromboxane Research. Vol. 4, Pg. 157, 1978.
rat LD50 intravenous 25100ug/kg (25.1mg/kg)   Advances in Prostaglandin and Thromboxane Research. Vol. 4, Pg. 157, 1978.