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Substance Name: Metenkefalin [INN]
RN: 58569-55-4
UNII: 9JEZ9OD3AS
InChIKey: YFGBQHOOROIVKG-FKBYEOEOSA-N

Note

  • One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.

Molecular Formula

  • C27-H35-N5-O7-S

Molecular Weight

  • 573.6675
 

Classification Code

  • Neurotransmitter Agents
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Names and Synonyms

Name of Substance

  • Enkephalin, methionine
  • Metenkefalin [INN]

MeSH Heading

  • Enkephalin, methionine

Synonyms

  • (Met5)-enkephalin
  • CCRIS 4225
  • EINECS 261-335-8
  • Enkephalin, methionine
  • Lupex
  • MET-enkephalin
  • Metenkefalin
  • NSC 374896
  • Opioid growth factor
  • Porcine beta-endorphin 1-5
  • Tyr-Gly-Gly-Phe-Met-OH
  • UNII-9JEZ9OD3AS

Systematic Names

  • 1-5-Adrenorphin (human)
  • Adrenorphin (human), 6-de-L-arginine-7-de-L-arginine-8-de-L-valinamide-
  • Methionine enkephalin
  • N-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-methionine

Registry Numbers

CAS Registry Number

  • 58569-55-4

FDA UNII

  • 9JEZ9OD3AS

System Generated Number

  • 0058569554

Structure Descriptors

InChI

1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1

InChIKey

YFGBQHOOROIVKG-FKBYEOEOSA-N

Smiles

CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)O