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Substance Name: Enkephalin, leucine
RN: 58822-25-6
UNII: RI01R707R6
InChIKey: URLZCHNOLZSCCA-VABKMULXSA-N

Note

  • One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.

Molecular Formula

  • C28-H37-N5-O7

Molecular Weight

  • 555.6283
 

Classification Code

  • Neurotransmitter Agents
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Names and Synonyms

Name of Substance

  • Enkephalin, leucine

MeSH Heading

  • Enkephalin, leucine

Synonyms

  • CCRIS 6338
  • EINECS 261-457-1
  • Enkephalin, leucine
  • Leu-enkephalin
  • Leucine enkephalin
  • Leucine-enkephalin
  • Leucyl-enkephalin
  • NSC 350588
  • UNII-RI01R707R6

Systematic Names

  • L-Leucine, N-(N-(N-(N-L-tyrosylglycyl)glycyl)-L-phenylalanyl)-
  • Leucine enkephalin
  • N-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-leucine

Registry Numbers

CAS Registry Number

  • 58822-25-6

FDA UNII

  • RI01R707R6

System Generated Number

  • 0058822256

Structure Descriptors

InChI

1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1

InChIKey

URLZCHNOLZSCCA-VABKMULXSA-N

Smiles

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)O