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Substance Name: Cyclizine dihydrochloride
RN: 5897-18-7
UNII: VF601QVZ67
InChIKey: CKLJCUGYMOMAEJ-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H22-N2.2Cl-H

Molecular Weight

  • 339.3076
 
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Names and Synonyms

Results Name

  • Cyclizine dihydrochloride

Name of Substance

  • Cyclizine dihydrochloride

Synonyms

  • 1-Diphenylmethyl-4-methylpiperazine dihydrochloride
  • Cyclizine dihydrochloride
  • Piperazine, 1-benzhydryl-4-methyl-, dihydrochloride
  • UNII-VF601QVZ67

Systematic Name

  • Piperazine, 1-diphenylmethyl-4-methyl-, dihydrochloride

Registry Numbers

CAS Registry Number

  • 5897-18-7

FDA UNII

  • VF601QVZ67

System Generated Number

  • 0005897187

Molecular Formulas

Molecular Formula

  • C18-H22-N2.2Cl-H

Molecular Formula Fragments

  • C18-H22-N2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C18H22N2.2ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;;/h2-11,18H,12-15H2,1H3;2*1H

InChIKey

CKLJCUGYMOMAEJ-UHFFFAOYSA-N

Smiles

CN1CCN(CC1)C(c2ccccc2)c3ccccc3.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 69mg/kg (69mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: EXCITEMENT
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 279, 1957.