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Substance Name: Folic acid [USP:INN:BAN:JAN]
RN: 59-30-3
UNII: 935E97BOY8
InChIKey: OVBPIULPVIDEAO-LBPRGKRZSA-N
Note
- A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Molecular Formula
- C19-H19-N7-O6
Molecular Weight
- 441.4021
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antiviral (COVID-19)
- Drug / Therapeutic Agent
- Growth Substances
- Hematinics
- Hematologic Agents
- Micronutrients
- Mutation Data
- Reproductive Effect
- Vitamin (Hematopoietic)
- Vitamin B Complex
- Vitamins
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Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Folic acid
- Folic acid [USP:INN:BAN:JAN]
- L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-
- N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
MeSH Heading
- Folic acid
Synonyms
- 4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)-
- Acfol (Spain)
- Acide folique
- Acide folique [INN-French]
- Acido folico
- Acido folico [INN-Spanish]
- Acidum folicum
- Acidum folicum [INN-Latin]
- Acifolic
- AI3-26387
- Antianemia factor
- CCRIS 666
- Cytofol
- EINECS 200-419-0
- Facid
- Factor U
- Folacid
- Folacin
- Folaemin
- Folaemin [Netherlands]
- Folan
- Folasic (Australia)
- Folate
- Folbal
- Folcidin
- Folcidin (VAN)
- Folcysteine
- Foldine
- Foldine [France]
- Folettes
- Foliamin
- Folic acid
- Folicet
- Folico
- Folico (Italy)
- Folina
- Folina (Italy)
- Folipac
- Folsan
- Folsaure
- Folsav
- Folvite
- Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, L-
- Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
- Glutamic acid, pteroyl-, L-
- HSDB 2002
- Incafolic
- Kyselina listova
- Kyselina listova [Czech]
- L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
- L-Glutamic acid, N-(4-((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
- Liver Lactobacillus casei factor
- Megafol
- Millafol
- Mittafol
- N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
- N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
- Neocepri
- Nifolin
- Nifolin [Denmark]
- Novofolacid
- Novofolacid [Canada]
- NSC 3073
- PGA
- PGA (VAN)
- Pteglu
- Pteroyl-L-glutamic acid
- Pteroyl-L-monoglutamic acid
- Pteroylglutamic acid
- Pteroylmonoglutamate
- Pteroylmonoglutamic acid
- UNII-935E97BOY8
- USAF CB-13
- Vitamin B11
- Vitamin B9
- Vitamin Bc
- Vitamin Be
- Vitamin M
Systematic Names
- Folic acid
- L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
- L-Glutamic acid, N-(4-(((2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
Superlist Name
- Folic acid
Mixture Name
- Mission Prenatal
Registry Numbers
CAS Registry Number
- 59-30-3
FDA UNII
- 935E97BOY8
Other Registry Numbers
- 11096-55-2
- 33609-88-0
Related Registry Numbers
- 36653-55-1 (mono-potassium salt)
- 6484-89-5 (mono-hydrochloride salt)
System Generated Number
- 0000059303
Structure Descriptors
InChI
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1InChIKey
OVBPIULPVIDEAO-LBPRGKRZSA-NSmiles
NC1=NC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intravenous | 120mg/kg (120mg/kg) | Drugs in Japan Vol. -, Pg. 1409, 1995. | |
mouse | LD50 | intraperitoneal | 85mg/kg (85mg/kg) | BEHAVIORAL: COMA BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Experientia. Vol. 41, Pg. 72, 1985. |
mouse | LD50 | intravenous | 282mg/kg (282mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. | |
mouse | LD50 | oral | 10gm/kg (10000mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. | |
mouse | LDLo | subcutaneous | 200mg/kg (200mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES BLOOD: CHANGES IN SPLEEN | Proceedings of the Society for Experimental Biology and Medicine. Vol. 71, Pg. 544, 1949. |
rabbit | LD50 | intravenous | 410mg/kg (410mg/kg) | Drugs in Japan Vol. -, Pg. 1409, 1995. | |
rat | LD50 | intravenous | 500mg/kg (500mg/kg) | Drugs in Japan Vol. -, Pg. 1409, 1995. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 250 dec | deg C | EXP | |
log P (octanol-water) | -2.810 | (none) | EST | |
Water Solubility | 1.6 | mg/L | 25 | EXP |
Vapor Pressure | 3.37E-21 | mm Hg | 25 | EST |
Henry's Law Constant | 3.55E-33 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 2.60E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.