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Substance Name: 2-Oxindole
RN: 59-48-3
UNII: 0S9338U62H
InChIKey: JYGFTBXVXVMTGB-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C8-H7-N-O

Molecular Weight

  • 133.1493
 
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Names and Synonyms

Name of Substance

  • 2-Oxindole

Synonyms

  • 1,3-Dihydro-2H-indol-2-one
  • 1,3-Dihydroindol-2-one
  • 2-Oxindole
  • 2-Oxindoline
  • 2-Oxoindoline
  • 5-21-08-00007 (Beilstein Handbook Reference)
  • BRN 0114692
  • EINECS 200-429-5
  • Indol-2(3H)-one
  • NSC 274863
  • Oxindol
  • Oxindole
  • UNII-0S9338U62H

Systematic Names

  • 1,3-Dihydro-2H-indol-2-one
  • 2,3-Dihydroindol-2-one
  • 2-Indolinone
  • 2H-Indol-2-one, 1,3-dihydro-
  • 2H-Indol-2-one, 1,3-dihydro- (9CI)

Registry Numbers

CAS Registry Number

  • 59-48-3

FDA UNII

  • 0S9338U62H

System Generated Number

  • 0000059483

Structure Descriptors

InChI

1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

InChIKey

JYGFTBXVXVMTGB-UHFFFAOYSA-N

Smiles

c1ccc2c(c1)CC(=O)N2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 400mg/kg (400mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 152, Pg. 121, 1964.
mouse LD50 oral 400mg/kg (400mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 152, Pg. 121, 1964.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 128 deg C   EXP
log P (octanol-water) 1.16 (none)   EXP
Water Solubility 9130 mg/L 25 EST
Vapor Pressure 1.32E-04 mm Hg 25 EST
Henry's Law Constant 2.26E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.56E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.