Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Gardimycin
RN: 59165-34-3
InChIKey: LAWKVNVCUPIOMG-HWWYPGLISA-N

Note

  • A globular type B lantibiotic; from actinoplanes.

Classification Codes

  • Antibiotics
  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • Unspecified

Molecular Weight

  • 1754.0508
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Gardimycin

Synonym

  • Antibiotic A 3802-IV-3

Systematic Names

  • Actagardina
  • Actagardine
  • Actagardinum
  • Gardimycin

Registry Numbers

CAS Registry Number

  • 59165-34-3

Other Registry Numbers

  • 165749-25-7
  • 251537-34-5

System Generated Number

  • 0059165343

Structure Descriptors

InChI

1S/C81H132N20O23/c1-20-40(12)63(79(121)89-45(17)67(109)86-44(16)68(110)90-47(19)81(123)124)101-78(120)62(39(10)11)99-72(114)50(22-3)91-58(103)34-84-66(108)43(15)87-76(118)57(36-102)92-59(104)35-85-70(112)56(32-48-33-83-53-28-26-25-27-49(48)53)97-77(119)61(38(8)9)98-69(111)46(18)88-71(113)51(23-4)93-74(116)54(29-30-60(105)106)95-80(122)64(41(13)21-2)100-73(115)52(24-5)94-75(117)55(31-37(6)7)96-65(107)42(14)82/h25-28,33,37-47,50-52,54-57,61-64,83,102H,20-24,29-32,34-36,82H2,1-19H3,(H,84,108)(H,85,112)(H,86,109)(H,87,118)(H,88,113)(H,89,121)(H,90,110)(H,91,103)(H,92,104)(H,93,116)(H,94,117)(H,95,122)(H,96,107)(H,97,119)(H,98,111)(H,99,114)(H,100,115)(H,101,120)(H,105,106)(H,123,124)/t40-,41-,42+,43+,44-,45+,46+,47+,50+,51+,52+,54+,55-,56+,57+,61-,62-,63-,64-/m0/s1

InChIKey

LAWKVNVCUPIOMG-HWWYPGLISA-N

Smiles

CC[C@H](C)[C@@H](C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](CC)C(=O)N[C@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc1c[nH]c2c1cccc2)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](C)C(=O)NCC(=O)N[C@H](CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)O)NC(=O)[C@@H](CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3310mg/kg (3310mg/kg)   Journal of Antibiotics. Vol. 38, Pg. 1506, 1985.
mouse LD50 intravenous 2gm/kg (2000mg/kg)   Japanese Kokai Tokyo Koho Patents. Vol. #76-51589,