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Substance Name: Lorzafone [INN]
RN: 59179-95-2
UNII: BI9KI838VI
InChIKey: RCPMGOCZIHMTRD-UHFFFAOYSA-N

Note

  • Used in the detection & analysis of pharmacologically active benzodiazepines.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H17-Cl2-N3-O3

Molecular Weight

  • 394.2563
 
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Names and Synonyms

Results Name

  • Lorzafone [INN]

Name of Substance

  • 2-(2-Chlorobenzoyl)-4-chloro-N-methyl-N'-glycylglycinanilide
  • Lorzafone anhydrous
  • Lorzafone [INN]

Synonyms

  • 45-0088S
  • 45-OO88S
  • Glycyl-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methylglycinamide
  • Lorzafona
  • Lorzafona [Spanish]
  • Lorzafone
  • Lorzafonum
  • Lorzafonum [Latin]
  • N-(4-Chloro-2-(2-chlorobenzoyl)phenyl)-glycyl-N-methylglycinamide
  • UNII-BI9KI838VI

Systematic Name

  • Glycinamide, glycyl-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-

Registry Numbers

CAS Registry Number

  • 59179-95-2

FDA UNII

  • BI9KI838VI

System Generated Number

  • 0059179952

Structure Descriptors

InChI

1S/C18H17Cl2N3O3/c1-23(17(25)10-22-16(24)9-21)15-7-6-11(19)8-13(15)18(26)12-4-2-3-5-14(12)20/h2-8H,9-10,21H2,1H3,(H,22,24)

InChIKey

RCPMGOCZIHMTRD-UHFFFAOYSA-N

Smiles

CN(c1ccc(cc1C(=O)c2ccccc2Cl)Cl)C(=O)CNC(=O)CN

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 1gm/kg (1000mg/kg) BEHAVIORAL: ANTIANXIETY

BEHAVIORAL: MUSCLE WEAKNESS
Journal of Medicinal Chemistry. Vol. 24, Pg. 20, 1981.