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Substance Name: Laurocapram [USAN:INN]
RN: 59227-89-3
UNII: 1F3X9DRV9X
InChIKey: AXTGDCSMTYGJND-UHFFFAOYSA-N

Note

  • Enhances percutaneous absorption of different chemicals.

Classification Codes

  • Drug / Therapeutic Agent
  • Pharmaceutic Aid (Excipient)

Molecular Formula

  • C18-H35-N-O

Molecular Weight

  • 281.48
 
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Names and Synonyms

Name of Substance

  • Laurocapram
  • Laurocapram [USAN:INN]

Synonyms

  • 1-Dodecylazacycloheptan-2-one
  • 1-Dodecylhexahydro-2H-azepin-2-one
  • 4-21-00-03206 (Beilstein Handbook Reference)
  • Azone
  • BRN 0167211
  • Caswell No. 064A
  • EINECS 261-668-9
  • HSDB 7660
  • Laurocapram
  • Laurocapramum
  • Laurocapramum [Latin]
  • N 0252
  • N-0252
  • N-Lauryl caprolactam
  • Tranzone
  • UNII-1F3X9DRV9X
  • USAF ND-72

Systematic Names

  • 2H-Azepin-2-one, 1-dodecylhexahydro-
  • 2H-Azepin-2-one, hexahydro-N-lauryl-
  • Laurocapram

Superlist Name

  • N-Dodecylcaprolactam

Registry Numbers

CAS Registry Number

  • 59227-89-3

FDA UNII

  • 1F3X9DRV9X

System Generated Number

  • 0059227893

Structure Descriptors

InChI

1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)20/h2-17H2,1H3

InChIKey

AXTGDCSMTYGJND-UHFFFAOYSA-N

Smiles

N1(C(CCCCC1)=O)CCCCCCCCCCCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 100mg/kg (100mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 8gm/kg (8000mg/kg)   Drug Development and Industrial Pharmacy. Vol. 9, Pg. 725, 1983.
mouse LD50 skin 8gm/kg (8000mg/kg)   Drug Development and Industrial Pharmacy. Vol. 9, Pg. 725, 1983.
rat LD50 intraperitoneal 8gm/kg (8000mg/kg)   Drug Development and Industrial Pharmacy. Vol. 9, Pg. 725, 1983.
rat LD50 intravenous 8gm/kg (8000mg/kg)   Drug Development and Industrial Pharmacy. Vol. 9, Pg. 725, 1983.
rat LD50 oral > 5gm/kg (5000mg/kg)   United States Patent Document. Vol. #4882359,
rat LD50 skin 8gm/kg (8000mg/kg)   Drug Development and Industrial Pharmacy. Vol. 9, Pg. 725, 1983.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   United States Patent Document. Vol. #4882359,
rat LD50 unreported 8gm/kg (8000mg/kg)   Archives of Dermatology. Vol. 118, Pg. 474, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -7.00E+00 deg C   EXP
log P (octanol-water) 6.280 (none)   EST
Atmospheric OH Rate Constant 4.66E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.