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Substance Name: Midazolam hydrochloride [USAN]
RN: 59467-96-8
UNII: W7TTW573JJ
InChIKey: PLYSCVSCYOQVRP-UHFFFAOYSA-N

Classification Codes

  • Anesthetic (Injectable)
  • Drug / Therapeutic Agent
  • Human Data

Molecular Formula

  • C18-H13-Cl-F-N3.Cl-H

Molecular Weight

  • 362.2336
 
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Names and Synonyms

Name of Substance

  • Midazolam hydrochloride
  • Midazolam hydrochloride [USAN]

Synonyms

  • 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine hydrochloride
  • Dormicum
  • EINECS 261-776-6
  • Hypnovel
  • Midazolam HCl
  • Midazolam hydrochloride
  • Midazolam hydrochloride preservative free
  • Ro 21-3981/003
  • Rocam
  • UNII-W7TTW573JJ
  • Versed

Systematic Names

  • 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, hydrochloride
  • 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, monohydrochloride
  • 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine monohydrochloride

Superlist Name

  • Midazolam hydrochloride

Registry Numbers

CAS Registry Number

  • 59467-96-8

FDA UNII

  • W7TTW573JJ

System Generated Number

  • 0059467968

Molecular Formulas

Molecular Formula

  • C18-H13-Cl-F-N3.Cl-H

Molecular Formula Fragments

  • C18-H13-Cl-F-N3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C18H13ClFN3.ClH/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;/h2-9H,10H2,1H3;1H

InChIKey

PLYSCVSCYOQVRP-UHFFFAOYSA-N

Smiles

Cl.Cc1ncc2CN=C(c3ccccc3F)c4cc(Cl)ccc4n12

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo intravenous 200ug/kg (0.2mg/kg)   British Medical Journal. Vol. 293, Pg. 822, 1986.
child TDLo intravenous 200ug/kg (0.2mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"

SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
British Medical Journal. Vol. 293, Pg. 822, 1986.
child TDLo intravenous 22mg/kg/4D-I (22mg/kg) LIVER: OTHER CHANGES

BLOOD: CHANGE IN CLOTTING FACTORS
British Medical Journal. Vol. 289, Pg. 799, 1984.
man TDLo intravenous 43ug/kg (0.043mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Annals of Emergency Medicine. Vol. 32, Pg. 263, 1998.
man TDLo intravenous 71ug/kg (0.071mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"

SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
British Medical Journal. Vol. 293, Pg. 822, 1986.