Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Bufuralol hydrochloride
RN: 59652-29-8
InChIKey: KJBONRGCLLBWCJ-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C16-H23-N-O2.Cl-H

Molecular Weight

  • 297.824
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Bufuralol hydrochloride

Synonyms

  • 1-(7-Aethylbenzofuran-2-yl)-2-tert-butylamino-1-hydroxyaethan-hydrochlorid
  • 1-(7-Aethylbenzofuran-2-yl)-2-tert-butylamino-1-hydroxyaethan-hydrochlorid [German]
  • 1-(7-Ethylbenzofuran-2-yl)-2-tert-butylamino-1-hydroxyethane hydrochloride
  • 2-tert-Butylamino-1-(7-ethyl-2-benzofuranyl)ethanol hydrochloride
  • Angium
  • Bufuralol HCl
  • Bufurolol hydrochloride
  • CCRIS 1056

Systematic Names

  • Bufurolol hydrochloride
  • Ethanol, 2-tert-butylamino-1-(7-ethyl-2-benzofuranyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 59652-29-8

Related Registry Number

  • 54340-62-4 (Parent)

System Generated Number

  • 0059652298

Molecular Formulas

Molecular Formula

  • C16-H23-N-O2.Cl-H

Molecular Formula Fragments

  • C16-H23-N-O2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C16H23NO2.ClH/c1-5-11-7-6-8-12-9-14(19-15(11)12)13(18)10-17-16(2,3)4;/h6-9,13,17-18H,5,10H2,1-4H3;1H

InChIKey

KJBONRGCLLBWCJ-UHFFFAOYSA-N

Smiles

C([C@@H](c1oc2c(c1)cccc2CC)O)NC(C)(C)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 88mg/kg (88mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1410, 1977.
mouse LD50 intravenous 29700ug/kg (29.7mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1410, 1977.
mouse LD50 oral 177mg/kg (177mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1410, 1977.
rat LD50 oral 750mg/kg (750mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1410, 1977.
rat LD50 subcutaneous 1400mg/kg (1400mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 1410, 1977.