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Substance Name: Metaraminol hydrochloride
RN: 5967-52-2
UNII: 90698QK27F
InChIKey: PPRPRPMMKPXRKK-YDYUUSCQSA-N

Note

  • A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.

Molecular Formula

  • C9-H13-N-O2.Cl-H

Molecular Weight

  • 203.6676
 

Classification Code

  • Drug / Therapeutic Agent
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Names and Synonyms

Name of Substance

  • Metaraminol hydrochloride

Synonyms

  • 1-(m-Hydroxyphenyl)-2-aminopropanol hydrochloride
  • 1-m-Hydroxyphenyl-2-amino-1-propanol hydrochloride
  • alpha-(1-Aminoethyl)-3-hydroxybenzyl alcohol hydrochloride
  • m-Oxynorephedrine hydrochloride
  • Metaraminol HCl
  • Metaraminol hydrochloride
  • Norephedrine, m-hydroxy-, hydrochloride
  • UNII-90698QK27F

Systematic Name

  • Benzyl alcohol, alpha-(1-aminoethyl)-m-hydroxy-, hydrochloride

Registry Numbers

CAS Registry Number

  • 5967-52-2

FDA UNII

  • 90698QK27F

System Generated Number

  • 0005967522

Molecular Formulas

Molecular Formula

  • C9-H13-N-O2.Cl-H

Molecular Formula Fragments

  • C9-H13-N-O2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C9H13NO2.ClH/c1-6(10)9(12)7-3-2-4-8(11)5-7;/h2-6,9,11-12H,10H2,1H3;1H/t6-,9-;/m0./s1

InChIKey

PPRPRPMMKPXRKK-YDYUUSCQSA-N

Smiles

C[C@@H]([C@@H](c1cccc(c1)O)O)N.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 440mg/kg (440mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 207, 1948.
rabbit LDLo intravenous 16mg/kg (16mg/kg)   Journal of the American Chemical Society. Vol. 53, Pg. 4149, 1931.
rat LDLo subcutaneous 40mg/kg (40mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 62, 1941.