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Substance Name: Citalopram hydrobromide [USAN:USP]
RN: 59729-32-7
UNII: I1E9D14F36
InChIKey: WIHMBLDNRMIGDW-UHFFFAOYSA-N

Note

  • A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.

Molecular Formula

  • C20-H21-F-N2-O.Br-H

Molecular Weight

  • 405.3088
 

Classification Codes

  • Antidepressant (Selective Serotonin Reuptake Inhibitor)
  • Selective Serotonin Reuptake Inhibitor

Names and Synonyms

Name of Substance

  • Citalopram hydrobromide
  • Citalopram hydrobromide [USAN:USP]

Synonyms

  • 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile monohydrobromide
  • 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, monohydrobromide
  • Celexa
  • Cipramil
  • Citalopram HBr
  • Citalopram hydrobromide
  • EINECS 261-890-6
  • Elopram
  • Lu 10-171-B
  • Seropram
  • UNII-I1E9D14F36

Systematic Name

  • 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile monohydrobromide

Registry Numbers

CAS Registry Number

  • 59729-32-7

FDA UNII

  • I1E9D14F36

System Generated Number

  • 0059729327

Molecular Formulas

Molecular Formula

  • C20-H21-F-N2-O.Br-H

Molecular Formula Fragments

  • Br-H
  • C20-H21-F-N2-O
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H

InChIKey

WIHMBLDNRMIGDW-UHFFFAOYSA-N

Smiles

Br.CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD intraperitoneal > 10mg/kg (10mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Journal of Neurochemistry. Vol. 69, Pg. 206, 1997.