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Substance Name: Paulomycin [USAN:INN]
RN: 59794-18-2
UNII: RW5242FF5Z
InChIKey: HYYDZRXDSYTIEH-MQTRCCAJSA-N

Note

  • From Streptomyces paulus; appears to be similar to senfolomycin and proceomycin but seems to have more nitrogen and sulfur; NMR indicates seven methyl groups and possible acetyl.

Molecular Weight

  • 658.6306
 

Classification Codes

  • Antibacterial
  • Drug / Therapeutic Agent
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Names and Synonyms

Name of Substance

  • Paulomycin [USAN:INN]
  • Volonomycin

Synonyms

  • Antibiotic U 43120
  • Paulomicina
  • Paulomicina [INN-Spanish]
  • Paulomycin
  • Paulomycin. An antibiotic obtained from cultures of Streptomyces paulus, variant
  • Paulomycine
  • Paulomycine [INN-French]
  • Paulomycinum
  • Paulomycinum [INN-Latin]
  • U-43,120
  • UNII-RW5242FF5Z
  • Volonomycin

Systematic Name

  • Paulomycin

Registry Numbers

CAS Registry Number

  • 59794-18-2

FDA UNII

  • RW5242FF5Z

System Generated Number

  • 0059794182

Structure Descriptors

InChI

1S/C27H34N2O15S/c1-5-12(29-9-45)26(37)44-21-15(8-40-11(3)30)42-24(27(38)7-13(31)18(28)17(23(27)34)25(35)36)20(33)22(21)43-16-6-14(39-4)19(32)10(2)41-16/h5,10,14-16,19-22,24,32-33,38H,6-8,28H2,1-4H3,(H,35,36)/b12-5-/t10-,14-,15-,16-,19+,20-,21-,22+,24?,27?/m1/s1

InChIKey

HYYDZRXDSYTIEH-MQTRCCAJSA-N

Smiles

C/C=C(/C(=O)O[C@@H]1[C@H](OC([C@@H]([C@@H]1O[C@@H]2C[C@H]([C@H]([C@H](O2)C)O)OC)O)C3(CC(=O)C(=C(C3=O)C(=O)O)N)O)COC(=O)C)\N=C=S

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD subcutaneous > 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 35, Pg. 285, 1982.