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Substance Name: 2-Mercaptoethanol
RN: 60-24-2
UNII: 14R9K67URN
InChIKey: DGVVWUTYPXICAM-UHFFFAOYSA-N
Note
- A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Molecular Formula
- C2-H6-O-S
Molecular Weight
- 78.1344
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Names and Synonyms
Name of Substance
- 2-Mercaptoethanol
- Mercaptoethanol
MeSH Heading
- Mercaptoethanol
Synonyms
- 1-Ethanol-2-thiol
- 1-Hydroxy-2-mercaptoethane
- 1-Mercapto-2-hydroxyethane
- 2-Hydroxy-1-ethanethiol
- 2-Hydroxyethanethiol
- 2-Hydroxyethyl mercaptan
- 2-ME
- 2-Mercapto-1-ethanol
- 2-Mercaptoethanol
- 2-Mercaptoethyl alcohol
- 2-Thioethanol
- 4-01-00-02428 (Beilstein Handbook Reference)
- AI3-07710
- beta-Hydroxyethanethiol
- beta-Hydroxyethylmercaptan
- BRN 0773648
- CCRIS 2097
- EC 200-464-6
- EINECS 200-464-6
- Emery 5791
- Ethanol, 2-mercapto-
- Ethylene glycol, monothio-
- HSDB 5199
- Hydroxyethyl mercaptan
- Mercaptoetanol
- Mercaptoethanol
- Monothioethylene glycol
- Monothioethyleneglycol
- Monothioglycol
- NSC 3723
- Thioethylene glycol
- Thioglycol
- Thiomonoglycol
- UNII-14R9K67URN
- USAF EK-4196
Systematic Names
- 2-Mercaptoethanol
- Ethanol, 2-mercapto-
Superlist Names
- 2-Mercaptoethanol
- Ethanol, 2-mercapto-
- Thioglycol
- Thioglycol [UN2966] [Poison]
- UN2966
Registry Numbers
CAS Registry Number
- 60-24-2
FDA UNII
- 14R9K67URN
Other Registry Number
- 99748-78-4
System Generated Number
- 0000060242
Structure Descriptors
InChI
InChI=1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2InChIKey
DGVVWUTYPXICAM-UHFFFAOYSA-NSmiles
OCCSToxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | skin | 300uL/kg (0.3mL/kg) | Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944. | |
| mouse | LC50 | inhalation | 13200mg/m3 (13200mg/m3) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971. |
| mouse | LD50 | intraperitoneal | 200mg/kg (200mg/kg) | National Technical Information Service. Vol. AD277-689, | |
| mouse | LD50 | oral | 190mg/kg (190mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: EXCITEMENT | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971. |
| mouse | LD50 | unreported | 480mg/kg (480mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR | Journal of Pharmaceutical Sciences. Vol. 62, Pg. 237, 1973. |
| rabbit | LD50 | skin | 150uL/kg (0.15mL/kg) | Union Carbide Data Sheet. Vol. 3/23/1973, | |
| rat | LCLo | inhalation | 250ppm/8H (250ppm) | Union Carbide Data Sheet. Vol. 3/23/1973, | |
| rat | LD50 | oral | 244mg/kg (244mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: EXCITEMENT | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | < 25 | deg C | EXP | |
| Boiling Point | 158 | deg C | EXP | |
| log P (octanol-water) | -0.200 | (none) | EST | |
| Water Solubility | 1.00E+06 | mg/L | EXP | |
| Atmospheric OH Rate Constant | 4.56E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.