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Substance Name: 2-Mercaptoethanol
RN: 60-24-2
UNII: 14R9K67URN
InChIKey: DGVVWUTYPXICAM-UHFFFAOYSA-N

Note

  • A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

Molecular Formula

  • C2-H6-O-S

Molecular Weight

  • 78.1344
 

Classification Codes

  • Mutation Data
  • Skin / Eye Irritant
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Names and Synonyms

Name of Substance

  • 2-Mercaptoethanol
  • Mercaptoethanol

MeSH Heading

  • Mercaptoethanol

Synonyms

  • 1-Ethanol-2-thiol
  • 1-Hydroxy-2-mercaptoethane
  • 1-Mercapto-2-hydroxyethane
  • 2-Hydroxy-1-ethanethiol
  • 2-Hydroxyethanethiol
  • 2-Hydroxyethyl mercaptan
  • 2-ME
  • 2-Mercapto-1-ethanol
  • 2-Mercaptoethanol
  • 2-Mercaptoethyl alcohol
  • 2-Thioethanol
  • 4-01-00-02428 (Beilstein Handbook Reference)
  • AI3-07710
  • beta-Hydroxyethanethiol
  • beta-Hydroxyethylmercaptan
  • BRN 0773648
  • CCRIS 2097
  • EC 200-464-6
  • EINECS 200-464-6
  • Emery 5791
  • Ethanol, 2-mercapto-
  • Ethylene glycol, monothio-
  • HSDB 5199
  • Hydroxyethyl mercaptan
  • Mercaptoetanol
  • Mercaptoethanol
  • Monothioethylene glycol
  • Monothioethyleneglycol
  • Monothioglycol
  • NSC 3723
  • Thioethylene glycol
  • Thioglycol
  • Thiomonoglycol
  • UNII-14R9K67URN
  • USAF EK-4196

Systematic Names

  • 2-Mercaptoethanol
  • Ethanol, 2-mercapto-

Superlist Names

  • 2-Mercaptoethanol
  • Ethanol, 2-mercapto-
  • Thioglycol
  • Thioglycol [UN2966] [Poison]
  • UN2966

Registry Numbers

CAS Registry Number

  • 60-24-2

FDA UNII

  • 14R9K67URN

Other Registry Number

  • 99748-78-4

System Generated Number

  • 0000060242

Structure Descriptors

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChIKey

DGVVWUTYPXICAM-UHFFFAOYSA-N

Smiles

C(CS)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 skin 300uL/kg (0.3mL/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.
mouse LC50 inhalation 13200mg/m3 (13200mg/m3) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971.
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 oral 190mg/kg (190mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971.
mouse LD50 unreported 480mg/kg (480mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: TREMOR		 Journal of Pharmaceutical Sciences. Vol. 62, Pg. 237, 1973.
rabbit LD50 skin 150uL/kg (0.15mL/kg)   Union Carbide Data Sheet. Vol. 3/23/1973,
rat LCLo inhalation 250ppm/8H (250ppm)   Union Carbide Data Sheet. Vol. 3/23/1973,
rat LD50 oral 244mg/kg (244mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(2), Pg. 56, 1971.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
Boiling Point 158 deg C   EXP
log P (octanol-water) -0.200 (none)   EST
Water Solubility 1.00E+06 mg/L   EXP
Atmospheric OH Rate Constant 4.56E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.