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Substance Name: Hexamethonium chloride
RN: 60-25-3
UNII: TIV4Q933FU
InChIKey: PYIHTIJNCRKDBV-UHFFFAOYSA-L

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C12-H30-N2.2Cl

Molecular Weight

  • 273.289
 
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Names and Synonyms

Results Name

  • Hexamethonium chloride

Name of Substance

  • Hexamethonium chloride

Synonyms

  • AI3-61433
  • alpha,omega-Bis(trimethylammonium)hexane dichloride
  • Ammonium, hexamethylenebis(trimethyl-, dichloride
  • Bistrium chloride
  • Chloor-hexaviet
  • Depressin
  • EINECS 200-465-1
  • Esomid chloride
  • Hestrium chloride
  • Hexamethionium chloride
  • Hexamethonium chloride
  • Hexamethonium dichloride
  • Hexamethylene(bistrimethylammonium)chloride
  • Hexamethylenebis(trimethylammonium) chloride
  • Hexameton chloride
  • Hexon chloride
  • Hexone chloride
  • Hiohex chloride
  • Methium chloride
  • Meton
  • NSC 21643
  • UNII-TIV4Q933FU

Systematic Names

  • 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride
  • 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2)
  • Ammonium, hexamethylenebis(trimethyl-, dichloride
  • Hexamethonium chloride

Registry Numbers

CAS Registry Number

  • 60-25-3

FDA UNII

  • TIV4Q933FU

Other Registry Number

  • 4277-80-9

Related Registry Number

  • 60-26-4 (Parent)

System Generated Number

  • 0000060253

Molecular Formulas

Molecular Formula

  • C12-H30-N2.2Cl

Molecular Formula Fragments

  • C12-H30-N2
  • Cl
  • COMPONENT

Structure Descriptors

InChI

1S/C12H30N2.2ClH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

InChIKey

PYIHTIJNCRKDBV-UHFFFAOYSA-L

Smiles

C[N+](C)(C)CCCCCC[N+](C)(C)C.[Cl-].[Cl-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 35mg/kg (35mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 346, 1957.
mouse LD50 intraperitoneal 62mg/kg (62mg/kg) AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 69, 1965.
mouse LD50 intravenous 26700ug/kg (26.7mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 127, Pg. 1, 1960.
rat LD50 intraperitoneal 100mg/kg (100mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 346, 1957.