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Substance Name: Methylhydrazine
RN: 60-34-4
UNII: UWA30B5Z1J
InChIKey: HDZGCSFEDULWCS-UHFFFAOYSA-N

Note

  • Hydrazine substituted by one methyl group.

Molecular Formula

  • C-H6-N2

Molecular Weight

  • 46.0724
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • Reportable Quantity (RQ) = 10 lb
  • skin; Ceiling 0.2 ppm (0.35 mg/m3); skin
  • Threshold Planning Quantity (TPQ) = 500 lb
  • TWA (0.01 ppm); skin; Confirmed animal carcinogen with relevance to humans

Names and Synonyms

Name of Substance

  • Methylhydrazine
  • Monomethylhydrazine

MeSH Heading

  • Monomethylhydrazine

Synonyms

  • 1-Methylhydrazine
  • 4-04-00-03322 (Beilstein Handbook Reference)
  • AI3-52240
  • BRN 0635645
  • CCRIS 394
  • EC 200-471-4
  • EINECS 200-471-4
  • HSDB 1172
  • Hydrazine, methyl-
  • Hydrazomethane
  • Methyl hydrazine
  • Methylhydrazine (mono)
  • Metylohydrazyna
  • Metylohydrazyna [Polish]
  • MMH
  • Monomethylhydrazine
  • RCRA waste number P068
  • UNII-UWA30B5Z1J

Systematic Names

  • Hydrazine, methyl-
  • Methylhydrazine

Superlist Names

  • Hydrazine, methyl-
  • Methyl hydrazine
  • Methylhydrazine
  • Methylhydrazine and its salts
  • Methylhydrazine [UN1244] [Poison]
  • Monomethylhydrazine
  • RCRA waste no. P068
  • UN1244

Registry Numbers

CAS Registry Number

  • 60-34-4

FDA UNII

  • UWA30B5Z1J

System Generated Number

  • 0000060344

Structure Descriptors

InChI

1S/CH6N2/c1-3-2/h3H,2H2,1H3

InChIKey

HDZGCSFEDULWCS-UHFFFAOYSA-N

Smiles

N(C)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LC50 inhalation 96ppm/1H (96ppm)   American Industrial Hygiene Association Journal. Vol. 31, Pg. 667, 1970.
dog LD50 intravenous 12mg/kg (12mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Proceedings of the Society for Experimental Biology and Medicine. Vol. 131, Pg. 226, 1969.
guinea pig LC50 inhalation 270mg/m3/4H (270mg/m3) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LIVER: LIVER FUNCTION TESTS IMPAIRED
"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 163, 1999.
guinea pig LD50 skin 48mg/kg (48mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Proceedings of the Society for Experimental Biology and Medicine. Vol. 131, Pg. 226, 1969.
hamster LC50 inhalation 143ppm/4H (143ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD AMA Archives of Industrial Health. Vol. 12, Pg. 609, 1955.
hamster LD50 intraperitoneal 21mg/kg (21mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
hamster LD50 oral 22mg/kg (22mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
hamster LD50 skin 239mg/kg (239mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
monkey LC50 inhalation 82ppm/1H (82ppm) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING
American Industrial Hygiene Association Journal. Vol. 31, Pg. 667, 1970.
mouse LC50 inhalation 56ppm/4H (56ppm) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
AMA Archives of Industrial Health. Vol. 12, Pg. 609, 1955.
mouse LD50 intraperitoneal 15mg/kg (15mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE
Proceedings of the Society for Experimental Biology and Medicine. Vol. 124, Pg. 172, 1967.
mouse LD50 intravenous 33200ug/kg (33.2mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 24, Pg. 71, 1973.
mouse LD50 oral 29mg/kg (29mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. AD-A125-539,
mouse LD50 subcutaneous 25mg/kg (25mg/kg)   British Journal of Cancer. Vol. 30, Pg. 429, 1974.
rabbit LD50 intravenous 12mg/kg (12mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Proceedings of the Society for Experimental Biology and Medicine. Vol. 131, Pg. 226, 1969.
rabbit LD50 skin 95mg/kg (95mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Proceedings of the Society for Experimental Biology and Medicine. Vol. 131, Pg. 226, 1969.
rat LC50 inhalation 34ppm/4H (34ppm)   Aerospace Medical Research Laboratory Report. Vol. TR-67-137, Pg. 1967,
rat LD50 intraperitoneal 21mg/kg (21mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
rat LD50 intravenous 17mg/kg (17mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
rat LD50 oral 32mg/kg (32mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD U.S. Army Chemical Warfare Laboratories. Vol. CWL,
rat LD50 skin 183mg/kg (183mg/kg)   Clinical Toxicology. Vol. 4, Pg. 435, 1971.
rat LD50 subcutaneous 35mg/kg (35mg/kg)   British Journal of Cancer. Vol. 30, Pg. 429, 1974.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -5.24E+01 deg C   EXP
Boiling Point 87.5 deg C   EXP
pKa Dissociation Constant 7.87 (none) 30 EXP
log P (octanol-water) -1.05E+00 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 50 mm Hg 25 EXP
Henry's Law Constant 3.03E-06 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 6.50E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.