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Substance Name: Cetylpyridinium chloride [USP:INN:BAN:JAN]
RN: 6004-24-6
UNII: D9OM4SK49P
InChIKey: NFCRBQADEGXVDL-UHFFFAOYSA-M
Note
- Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.
Molecular Formula
- C21-H38-N.Cl.H2-O
Molecular Weight
- 358.006
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Anti-Infective, Topical
- Drug / Therapeutic Agent
- Pharmaceutic Aid (Preservative)
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Names and Synonyms
Name of Substance
- Cetylpyridinium chloride [USP:INN:BAN:JAN]
Synonyms
- 1-Hexadecylpyridinium chloride monohydrate
- Ceepryn
- Cepacol
- Cetylpyridinium chloride
- Cetylpyridinium chloride monohydrate
- UNII-D9OM4SK49P
Systematic Name
- Pyridinium, 1-hexadecyl-, chloride, monohydrate
Registry Numbers
CAS Registry Number
- 6004-24-6
FDA UNII
- D9OM4SK49P
System Generated Number
- 0006004246
Molecular Formulas
Molecular Formula
- C21-H38-N.Cl.H2-O
Molecular Formula Fragments
- C21-H38-N
- Cl
- COMPONENT
- H2-O
Structure Descriptors
InChI
1S/C21H38N.ClH.H2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H;1H2/q+1;;/p-1InChIKey
NFCRBQADEGXVDL-UHFFFAOYSA-MSmiles
[n+]1(ccccc1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 100mg/kg (100mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
guinea pig | LDLo | intraperitoneal | 5mg/kg (5mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
mouse | LDLo | intraperitoneal | 3mg/kg (3mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
rabbit | LDLo | intraperitoneal | 5mg/kg (5mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
rabbit | LDLo | intravenous | 20mg/kg (20mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
rabbit | LDLo | oral | 400mg/kg (400mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
rabbit | LDLo | subcutaneous | 200mg/kg (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |
rat | LDLo | intraperitoneal | 15mg/kg (15mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 401, 1942. |