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Substance Name: Gabapentin [USAN:USP:INN:BAN]
RN: 60142-96-3
UNII: 6CW7F3G59X
InChIKey: UGJMXCAKCUNAIE-UHFFFAOYSA-N
Note
- A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
Molecular Formula
- C9-H17-N-O2
Molecular Weight
- 171.2383
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- Names & Synonyms
- Registry Numbers
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- Physical Properties
Classification Codes
- Analgesics
- Anti-Anxiety Agents
- Anti-Dyskinesia Agents
- Anticonvulsant
- Anticonvulsants
- Antimanic Agents
- Antiparkinson Agents
- Calcium Channel Blockers
- Cardiovascular Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Excitatory Amino Acid Agents
- Excitatory Amino Acid Antagonists
- Membrane Transport Modulators
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Psychotropic Drugs
- Sensory System Agents
- Tranquilizing Agents
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Names and Synonyms
Name of Substance
- Gabapentin
- Gabapentin [USAN:USP:INN:BAN]
MeSH Heading
- Gabapentin
Synonyms
- 1-(Aminomethyl)cyclohexaneacetic acid
- Aclonium
- BRN 2359739
- CCRIS 7210
- CI 945
- CI-945
- DM-1796
- DM-5689
- EINECS 262-076-3
- Fanatrex
- Gabapentin
- Gabapentine
- Gabapentine [INN-French]
- Gabapentino
- Gabapentino [INN-Spanish]
- Gabapentino [Spanish]
- Gabapentinum
- Gabapentinum [INN-Latin]
- Gabapetin
- Go 3450
- GOE 2450
- GOE 3450
- Gralise
- HSDB 7364
- Neuontin
- Neurontin
- NSC 742194
- NSC 759254
- Sefelsa
- Serada
- Therapentin-90
- UNII-6CW7F3G59X
- Vultin
Systematic Names
- Cyclohexaneacetic acid, 1-(aminomethyl)-
- Gabapentin
Registry Numbers
CAS Registry Number
- 60142-96-3
FDA UNII
- 6CW7F3G59X
System Generated Number
- 0060142963
Structure Descriptors
InChI
InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)InChIKey
UGJMXCAKCUNAIE-UHFFFAOYSA-NSmiles
NCC1(CC(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intravenous | > 1gm/kg (1000mg/kg) | Drugs of the Future. Vol. 11, Pg. 518, 1986. | |
| mouse | LD | oral | > 8053mg/kg (8053mg/kg) | Drugs of the Future. Vol. 9, Pg. 418, 1984. | |
| rat | LD | intravenous | > 2gm/kg (2000mg/kg) | Drugs of the Future. Vol. 11, Pg. 518, 1986. | |
| rat | LD | oral | > 8gm/kg (8000mg/kg) | Drugs of the Future. Vol. 11, Pg. 518, 1986. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | -1.10E+00 | (none) | EXP | |
| Water Solubility | 4490 | mg/L | 25 | EST |
| Vapor Pressure | 2.94E-10 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.81E-10 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 4.01E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.