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Substance Name: Lofentanil
RN: 60645-00-3
InChIKey: IMYHGORQCPYVBZ-UHFFFAOYSA-N

Molecular Formula

  • C25-H32-N2-O3

Molecular Weight

  • 408.5388
 
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Names and Synonyms

Name of Substance

  • Lofentanil
  • Lofentanil [Non stereospecific]

Synonyms

  • 4-piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenyleethyl)-, methyl ester, (3r,4s)-rel-(-)-
  • 4-piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-, methyl ester, cis-(-)-
  • HSDB 8378
  • Lofentanila
  • Lofentanilum
  • Methyl cis-(-)-3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate
  • R 32792

Systematic Name

  • 4-Piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-, methyl ester

Registry Numbers

CAS Registry Number

  • 60645-00-3

System Generated Number

  • 0060645003

Structure Descriptors

InChI

1S/C25H32N2O3/c1-4-23(28)27(22-13-9-6-10-14-22)25(24(29)30-3)16-18-26(19-20(25)2)17-15-21-11-7-5-8-12-21/h5-14,20H,4,15-19H2,1-3H3

InChIKey

IMYHGORQCPYVBZ-UHFFFAOYSA-N

Smiles

CCC(=O)N(c1ccccc1)C2(CCN(CCc3ccccc3)CC2C)C(=O)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intravenous 200ug/kg (0.2mg/kg) BEHAVIORAL: ANALGESIA Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1548, 1976.