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Substance Name: Trimethoprim hydrochloride
RN: 60834-30-2
UNII: 9XE000OU9B
InChIKey: YLCCEQZHUHUYPA-UHFFFAOYSA-N
Note
- A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
Molecular Formula
- C14-H18-N4-O3.Cl-H
Molecular Weight
- 326.782
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Names and Synonyms
Name of Substance
- Trimethoprim hydrochloride
Synonyms
- EINECS 262-450-6
- Primsol
- Proloprim
- Trimethoprim HCl
- Trimplex
- Trimplex 200
- UNII-9XE000OU9B
Systematic Name
- 5-((3,4,5-Trimethoxyphenyl)methyl)pyrimidine-2,4-diamine hydrochloride
Registry Numbers
CAS Registry Number
- 60834-30-2
FDA UNII
- 9XE000OU9B
System Generated Number
- 0060834302
Molecular Formulas
Molecular Formula
- C14-H18-N4-O3.Cl-H
Molecular Formula Fragments
- C14-H18-N4-O3
- Cl-H
- COMPONENT