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Substance Name: N,N-Dimethyltryptamine
RN: 61-50-7
UNII: WUB601BHAA
InChIKey: DMULVCHRPCFFGV-UHFFFAOYSA-N
Note
- An N-methylated indoleamine derivative and serotonergic hallucinogen which occurs naturally and ubiquitously in several plant species including Psychotria veridis. It also occurs in trace amounts in mammalian brain, blood, and urine, and is known to act as an agonist or antagonist of certain SEROTONIN RECEPTORS.
Molecular Formula
- C12-H16-N2
Molecular Weight
- 188.2724
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Central Nervous System Agents
- Drug / Therapeutic Agent
- Hallucinogens
- Human Data
- Neurotransmitter Agents
- Psychotropic Drugs
- Serotonin Agents
- Serotonin Antagonists
- Serotonin Receptor Agonists
Superlist Classification Code
- DEA Schedule I
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Names and Synonyms
Name of Substance
- N,N-Dimethyltryptamine
MeSH Heading
- N,N-Dimethyltryptamine
Synonyms
- 2-(3-Indolyl)ethyldimethylamine
- 3-(2-Dimethylaminoethyl)indole
- 5-22-10-00048 (Beilstein Handbook Reference)
- BRN 0138259
- DMT (psychogenic)
- EINECS 200-508-4
- HSDB 8017
- N,N-Dimethyltryptamine
- NSC 63795
- UNII-WUB601BHAA
Systematic Names
- 1H-Indole-3-ethanamine, N,N-dimethyl- (9CI)
- Indole, 3-(2-(dimethylamino)ethyl)-
- N,N-Dimethyl-1H-indole-3-ethylamine
Superlist Names
- DEA No. 7435
- Dimethyltryptamine
- DMT
Registry Numbers
CAS Registry Number
- 61-50-7
FDA UNII
- WUB601BHAA
Other Registry Number
- 68677-25-8
System Generated Number
- 0000061507
Structure Descriptors
InChI
InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3InChIKey
DMULVCHRPCFFGV-UHFFFAOYSA-NSmiles
CN(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
man | TDLo | intramuscular | 1mg/kg (1mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION | Psychopharmacologia Vol. 4, Pg. 39, 1963. |
mouse | LD50 | intraperitoneal | 47mg/kg (47mg/kg) | Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1620, 1974. | |
mouse | LD50 | intravenous | 32mg/kg (32mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00740, |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 46 | deg C | EXP | |
pKa Dissociation Constant | 8.68 | (none) | EXP | |
log P (octanol-water) | 1.940 | (none) | EST | |
Water Solubility | 1.12E+04 | mg/L | 25 | EST |
Vapor Pressure | 1.04E-04 | mm Hg | 25 | EST |
Henry's Law Constant | 6.44E-10 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 2.80E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.