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Substance Name: Levothyroxine sodium pentahydrate
RN: 6106-07-6
UNII: 9J765S329G
InChIKey: JMHCCAYJTTWMCX-QWPJCUCISA-M

Note

  • Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Molecular Formula

  • C15-H10-I4-N-O4.Na.5H2-O

Molecular Weight

  • 888.911
 

Classification Code

  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Levothyroxine sodium pentahydrate

Synonyms

  • Alanine, 3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-, monosodium salt, pentahydrate
  • O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine sodium salt pentahydrate
  • Sodium L-thyroxine pentahydrate
  • UNII-9J765S329G

Systematic Name

  • L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt, pentahydrate

Registry Numbers

CAS Registry Number

  • 6106-07-6

FDA UNII

  • 9J765S329G

System Generated Number

  • 0006106076

Molecular Formulas

Molecular Formula

  • C15-H10-I4-N-O4.Na.5H2-O

Molecular Formula Fragments

  • C15-H10-I4-N-O4
  • COMPONENT
  • H2-O
  • Na

Structure Descriptors

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChIKey

JMHCCAYJTTWMCX-QWPJCUCISA-M

Smiles

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)[O-]