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Substance Name: Cefonicid [INN:BAN]
RN: 61270-58-4
UNII: 6532B86WFG
InChIKey: DYAIAHUQIPBDIP-AXAPSJFSSA-N

Note

  • A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Molecular Formula

  • C18-H18-N6-O8-S3

Molecular Weight

  • 542.5722
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Drug / Therapeutic Agent
  • Human Data
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Names and Synonyms

Name of Substance

  • Cefonicid
  • Cefonicid [INN:BAN]

MeSH Heading

  • Cefonicid

Synonyms

  • BRN 1066181
  • Cefonicid
  • Cefonicido
  • Cefonicido [INN-Spanish]
  • Cefonicidum
  • Cefonicidum [INN-Latin]
  • UNII-6532B86WFG

Systematic Name

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6-alpha,7-beta(R*)))-

Registry Numbers

CAS Registry Number

  • 61270-58-4

FDA UNII

  • 6532B86WFG

Related Registry Number

  • 61270-78-8 (di-hydrochloride salt)

System Generated Number

  • 0061270584

Structure Descriptors

InChI

1S/C18H18N6O8S3/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32)/t11-,13-,16-/m1/s1

InChIKey

DYAIAHUQIPBDIP-AXAPSJFSSA-N

Smiles

c1ccc(cc1)[C@H](C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CSc4nnnn4CS(=O)(=O)O)C(=O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 40mg/kg/2D-I (40mg/kg) KIDNEY, URETER, AND BLADDER: HEMATURIA

BLOOD: TUMORS

BLOOD: HEMORRHAGE
Annals of Internal Medicine. Vol. 123, Pg. 472, 1995.