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Substance Name: Mecamylamine [INN]
RN: 6147-18-8
UNII: 6EE945D3OK
InChIKey: IMYZQPCYWPFTAG-NGZCFLSTSA-N

Note

  • A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Molecular Formula

  • C11-H21-N

Molecular Weight

  • 167.2939
 

Classification Codes

  • Antihypertensive Agents
  • Cardiovascular Agents
  • Cholinergic Agents
  • Cholinergic Antagonists
  • Ganglionic Blockers
  • Neurotransmitter Agents
  • Nicotinic Antagonists
  • Peripheral Nervous System Agents
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Names and Synonyms

Results Name

  • Mecamylamine [INN]

Name of Substance

  • Mecamylamine

MeSH Heading

  • Mecamylamine

Synonyms

  • (1RS,2SR,4SR)-N,2,3,3-Tetramethylbicyclo(2.2.1)heptan-2-amine
  • Bicyclo(2.2.1)heptan-2-amine, N,2,3,3-tetramethyl-
  • Mecamylamine
  • Mecamylamine [INN]
  • Mecamylamine [MI]
  • Mecamylamine [VANDF]
  • Mecamylamine [WHO-DD]
  • N,2,3,3-Tetramethyl-2-norbornanamine
  • UNII-6EE945D3OK

Registry Numbers

CAS Registry Number

  • 6147-18-8

FDA UNII

  • 6EE945D3OK

System Generated Number

  • 0006147188

Structure Descriptors

InChI

InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3/t8-,9+,11-/m0/s1

InChIKey

IMYZQPCYWPFTAG-NGZCFLSTSA-N

Smiles

CN[C@@]1(C)[C@@H]2CC[C@@H](C2)C1(C)C