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Substance Name: Tusukal
RN: 6159-39-3
InChIKey: MKAXSYNOZMOVDG-UHFFFAOYSA-N

Classification Codes

  • Antitussive
  • Drug / Therapeutic Agent

Molecular Formula

  • C20-H25-N-O.Cl-H

Molecular Weight

  • 331.884
 
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Names and Synonyms

Results Name

  • Tusukal

Synonyms

  • 1,1-Diphenyl-2-piperidino-propanol-(1) hydrochlorid
  • 1,1-Diphenyl-2-piperidino-propanol-(1) hydrochlorid [German]
  • Benzyl alcohol, alpha-phenyl-alpha-(1-(piperidino)ethyl)-, hydrochloride
  • HOE 10682
  • Tusukal

Systematic Name

  • 1-Piperidineethanol, beta-methyl-alpha,alpha-diphenyl-, hydrochloride

Registry Numbers

CAS Registry Number

  • 6159-39-3

System Generated Number

  • 0006159393

Molecular Formulas

Molecular Formula

  • C20-H25-N-O.Cl-H

Molecular Formula Fragments

  • C20-H25-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C20H25NO.ClH/c1-17(21-15-9-4-10-16-21)20(22,18-11-5-2-6-12-18)19-13-7-3-8-14-19;/h2-3,5-8,11-14,17,22H,4,9-10,15-16H2,1H3;1H

InChIKey

MKAXSYNOZMOVDG-UHFFFAOYSA-N

Smiles

N1(CCCCC1)[C@@H](C(O)(c1ccccc1)c1ccccc1)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 40mg/kg (40mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.
mouse LD50 oral 750mg/kg (750mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.
mouse LD50 subcutaneous 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.
rabbit LD50 intravenous 12500ug/kg (12.5mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.
rabbit LD50 subcutaneous 250mg/kg (250mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.
rat LD50 intravenous 25mg/kg (25mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 94, 1959.