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Substance Name: Racemomycin A, hydrochloride
RN: 6160-33-4
InChIKey: CCCBINNSRXNYDB-TWRCRAKCSA-N

Note

  • A group of antibiotic aminoglycosides differing only in the number of repeating residues in the peptide side chain. They are produced by Streptomyces and Actinomyces and may have broad spectrum antimicrobial and some antiviral properties.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H34-N8-O8.Cl-H

Molecular Weight

  • 538.987
 
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Names and Synonyms

Synonyms

  • Antibiotic R 4-A hydrochloride
  • Streptothricin hydrochloride

Systematic Names

  • Racemomycin A, hydrochloride
  • Streptothricin F, monohydrochloride (9CI)

Registry Numbers

CAS Registry Number

  • 6160-33-4

System Generated Number

  • 0006160334

Molecular Formulas

Molecular Formula

  • C19-H34-N8-O8.Cl-H

Molecular Formula Fragments

  • C19-H34-N8-O8
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H34N8O8.ClH/c20-3-1-2-7(21)4-10(30)24-13-14(31)15(35-18(22)33)9(6-28)34-17(13)27-19-25-11-8(29)5-23-16(32)12(11)26-19;/h7-9,11-15,17,28-29,31H,1-6,20-21H2,(H2,22,33)(H,23,32)(H,24,30)(H2,25,26,27);1H/t7-,8+,9+,11+,12-,13+,14-,15-,17+;/m0./s1

InChIKey

CCCBINNSRXNYDB-TWRCRAKCSA-N

Smiles

N1C[C@H]([C@H]2NC(=N[C@H]2C1=O)N[C@@H]1O[C@H](CO)[C@@H]([C@H](O)[C@H]1NC(=O)C[C@@H](N)CCCN)OC(=O)N)O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intraperitoneal 500mg/kg (500mg/kg) LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 176, 1974.
mouse LDLo intravenous 130mg/kg (130mg/kg)   Journal of Antibiotics. Vol. 27, Pg. 535, 1974.