Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Thiourea
RN: 62-56-6
UNII: GYV9AM2QAG
InChIKey: UMGDCJDMYOKAJW-UHFFFAOYSA-N

Note

  • A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.

Molecular Formula

  • C-H4-N2-S

Molecular Weight

  • 76.1226
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Drug / Therapeutic Agent
  • Fungicide, Bactericide, Wood Preservative
  • Human Data
  • Indicators and Reagents
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data
  • Unspecified / Unclassified Pesticide

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 10 lb

Names and Synonyms

Name of Substance

  • Thiourea

MeSH Heading

  • Thiourea

Synonyms

  • 2-Thiopseudourea
  • 2-Thiourea
  • AI3-03582
  • beta-Thiopseudourea
  • Caswell No. 855
  • CCRIS 588
  • EC 200-543-5
  • EINECS 200-543-5
  • EPA Pesticide Chemical Code 080201
  • HSDB 1401
  • Isothiourea
  • NSC 5033
  • Pseudothiourea
  • Pseudourea, 2-thio-
  • RCRA waste number U219
  • Sulourea
  • Thiocarbamide
  • Thiocarbonic acid diamide
  • Thiomocovina
  • Thiomocovina [Czech]
  • Thiourea
  • Thiuronium
  • THU
  • Tsizp 34
  • UNII-GYV9AM2QAG
  • Urea, 2-thio-
  • Urea, thio-
  • USAF EK-497

Systematic Names

  • Thiourea
  • Urea, 2-thio-
  • Urea, thio- (8CI)

Superlist Names

  • RCRA waste no. U219
  • Thiourea
  • Urea, thio-

Registry Numbers

CAS Registry Number

  • 62-56-6

FDA UNII

  • GYV9AM2QAG

Other Registry Numbers

  • 1032826-45-1
  • 1429623-74-4
  • 1803177-22-1

System Generated Number

  • 0000062566

Structure Descriptors

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChIKey

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Smiles

C(N)(N)=S

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 10gm/kg (10000mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 177, 1959.
guinea pig LDLo subcutaneous 4gm/kg (4000mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 177, 1959.
mammal (species unspecified) LD50 intraperitoneal 3500mg/kg (3500mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(3), Pg. 42, 1986.
mammal (species unspecified) LDLo oral 1gm/kg (1000mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(3), Pg. 42, 1986.
man LDLo unreported 147mg/kg (147mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 intraperitoneal 100mg/kg (100mg/kg)   National Technical Information Service. Vol. AD277-689,
rabbit LDLo oral 6985mg/kg (6985mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 177, 1959.
rat LD50 intraperitoneal 436mg/kg (436mg/kg)   Food and Cosmetics Toxicology. Vol. 3, Pg. 597, 1965.
rat LD50 oral 125mg/kg (125mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 177, 1959.
women TDLo oral 1660mg/kg/5W (1660mg/kg) BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)

BLOOD: GRANULOCYTOPENIA

BLOOD: HEMORRHAGE
Lancet. Vol. 246, Pg. 179, 1944.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 182 deg C   EXP
pKa Dissociation Constant 2.03 (none) 25 EXP
log P (octanol-water) -1.08E+00 (none)   EXP
Water Solubility 1.42E+05 mg/L 25 EXP
Henry's Law Constant 1.98E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 4.20E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.