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Substance Name: Dichlorvos [USAN:INN:BAN]
RN: 62-73-7
UNII: 7U370BPS14
InChIKey: OEBRKCOSUFCWJD-UHFFFAOYSA-N

Note

  • An organophosphorus insecticide that inhibits acetylcholinesterase.

Molecular Formula

  • C4-H7-Cl2-O4-P

Molecular Weight

  • 220.9753
 

Classification Codes

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Anthelmintic
  • Anthelmintics
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Cholinergic Agents
  • Cholinesterase Inhibitors
  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Fungicide, Bactericide, Wood Preservative
  • Insecticide
  • Insecticides
  • Mutation Data
  • Neurotransmitter Agents
  • Pesticides
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 240
  • 2011 CERCLA Priority List, Rank: 193
  • Reportable Quantity (RQ) = 10 lb
  • Threshold Planning Quantity (TPQ) = 1000 lb
  • TWA (0.1 mg/m3, vapor and aerosol, inhalable fraction); Skin; Sensitizer; Not classifiable as a human carcinogen; BEI
  • TWA 1 mg/m3; skin

Names and Synonyms

Name of Substance

  • Dichlorvos
  • Dichlorvos [BSI:ISO]
  • Dichlorvos [USAN:INN:BAN]

MeSH Heading

  • Dichlorvos

Synonyms

  • (2,2-Dichloor-vinyl)-dimethyl-fosfaat
  • (2,2-Dichloor-vinyl)-dimethyl-fosfaat [Dutch]
  • (2,2-Dichlor-vinyl)-dimethyl-phosphat
  • (2,2-Dichlor-vinyl)-dimethyl-phosphat [German]
  • (2,2-Dichloro-vinil)dimetil-fosfato
  • (2,2-Dichloro-vinil)dimetil-fosfato [Italian]
  • 2,2-Dichloroethenyl dimethyl phosphate
  • 2,2-Dichloroethenyl phosphoric acid dimethyl ester
  • 2,2-Dichlorovinyl dimethyl phosphate
  • 4-01-00-02063 (Beilstein Handbook Reference)
  • AI3-20738
  • Apavap
  • Astrobot
  • Atgard
  • Atgard C
  • Atgard V
  • BAY-19149
  • BAY-b 4986
  • Bayer 19149
  • Benfos
  • Bibesol
  • Brevinyl
  • Brevinyl E50
  • BRN 1709141
  • Canogard
  • Caswell No. 328
  • CCRIS 230
  • Chlorvinphos
  • Cypona
  • DDVP
  • DDVP (insecticide)
  • Dedevap
  • Denkavepon
  • Deriban
  • Derribante
  • Des (phosphate)
  • Devikol
  • Dichlofos
  • Dichloorvo
  • Dichloorvo [Dutch]
  • Dichlorfos
  • Dichlorfos [Polish]
  • Dichlorman
  • Dichlorophos
  • Dichlorovos
  • Dichlorphos
  • Dichlorvos
  • Dichlorvosum
  • Dichlorvosum [INN-Latin]
  • Diclorvos
  • Diclorvos [INN-Spanish]
  • Dimethyl 2,2-dichloroethenyl phosphate
  • Dimethyl 2,2-dichlorovinyl phosphate
  • Dimethyldichlorovinyl phosphate
  • Divipan
  • EINECS 200-547-7
  • ENT 20738
  • EPA Pesticide Chemical Code 084001
  • Equigard
  • Equigel
  • Estrosel
  • Estrosol
  • Ethenol, 2,2-dichloro-, dimethyl phosphate
  • Fecama
  • Fekama
  • Fly fighter
  • Fly-Die
  • Herkal
  • Herkol
  • HSDB 319
  • Insectigas D
  • Krecalvin
  • Lindanmafu
  • MAFU strip
  • Marvex
  • Mopari
  • NCI-C00113
  • Nefrafos
  • Nerkol
  • NO-Pest
  • NO-Pest strip
  • Nogos
  • Nogos 50
  • Nogos 50 EC
  • Nogos G
  • Novotox
  • NSC 6738
  • NSC-6738
  • Nuvan
  • Nuvan 100EC
  • Nuvan 7
  • O,O-Dimethyl 2,2-dichlorovinyl phosphate
  • O,O-Dimethyl dichlorovinyl phosphate
  • O,O-Dimethyl O-2,2-dichlorovinyl phosphate
  • O,O-Dimethyl-O-(2,2-dichlor-vinyl)-phosphat
  • O,O-Dimethyl-O-(2,2-dichlor-vinyl)-phosphat [German]
  • O,O-Dwumetylo-O-dwuchlorowinylofosforan
  • O,O-Dwumetylo-O-dwuchlorowinylofosforan [Polish]
  • O-(2,2-Dichlorvinyl)-O,O-dimethylphosphat
  • O-(2,2-Dichlorvinyl)-O,O-dimethylphosphat [German]
  • OMS 14
  • Panaplate
  • Phosphate de dimethyle et de 2,2-dichlorovinyle
  • Phosphate de dimethyle et de 2,2-dichlorovinyle [French]
  • Phosvit
  • SD 1750
  • SD-1750
  • Szklarniak
  • TAP 9VP
  • Task
  • TASK Tabs
  • Tenac
  • Tetravos
  • Unifos
  • Unifos (pesticide)
  • Unifos 50 EC
  • UNII-7U370BPS14
  • Uniphos
  • Unitox
  • Vapona
  • Vapona insecticide
  • Vaponite
  • Vapora II
  • Vinyl alcohol, 2,2-dichloro-, dimethyl phosphate
  • Vinylofos
  • Vinylophos
  • Winylophos
  • XLP 30

Systematic Names

  • Dichlorvos
  • Phosphoric acid, 2,2-dichloroethenyl dimethyl ester
  • Phosphoric acid, 2,2-dichlorovinyl dimethyl ester

Superlist Names

  • DDVP
  • Dichlorvos
  • Phosphoric acid, 2,2-dichloroethenyl dimethyl ester
  • Phosphoric acid, 2,2-dichlorovinyl dimethyl ester

Registry Numbers

CAS Registry Number

  • 62-73-7

FDA UNII

  • 7U370BPS14

Other Registry Numbers

  • 11095-17-3
  • 11096-21-2
  • 11111-31-2
  • 11111-44-7
  • 11126-72-0
  • 116788-91-1
  • 12772-40-6
  • 55819-32-4
  • 62139-95-1
  • 62655-59-8
  • 8023-22-1
  • 8072-21-7
  • 8072-39-7
  • 8076-16-2
  • 95828-55-0

System Generated Number

  • 0000062737

Structure Descriptors

InChI

1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3

InChIKey

OEBRKCOSUFCWJD-UHFFFAOYSA-N

Smiles

COP(=O)(OC)OC=C(Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 12mg/kg (12mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
chicken LD50 oral 6450ug/kg (6.45mg/kg)   Indian Journal of Pharmacology. Vol. 10, Pg. 323, 1978.
dog LD50 oral 100mg/kg (100mg/kg)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A141, Pg. 1984,
dog LDLo intravenous 2200ug/kg (2.2mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: NAUSEA OR VOMITING
Australian Veterinary Journal. Vol. 49, Pg. 113, 1973.
duck LD50 oral 7800ug/kg (7.8mg/kg)   Down to Earth. Vol. 35, Pg. 25, 1979.
hamster LD50 intraperitoneal 30mg/kg (30mg/kg)   Archives of Toxicology. Vol. 58, Pg. 152, 1986.
mammal (species unspecified) LD50 unreported 125mg/kg (125mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(8), Pg. 82, 1976.
mouse LC50 inhalation 13mg/m3/4H (13mg/m3) BEHAVIORAL: TREMOR

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(12), Pg. 35, 1968.
mouse LD50 intraperitoneal 22mg/kg (22mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 11, Pg. 91, 1963.
mouse LD50 intravenous 18mg/kg (18mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00004,
mouse LD50 oral 61mg/kg (61mg/kg)   Osaka Shiritsu Daigaku Igaku Zasshi. Journal of the Osaka City Medical Center. Vol. 15, Pg. 553, 1966.
mouse LD50 skin 206mg/kg (206mg/kg)   Agricultural and Biological Chemistry. Vol. 27, Pg. 684, 1963.
mouse LD50 subcutaneous 24mg/kg (24mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Industrial Medicine and Surgery. Vol. 31, Pg. 170, 1962.
mouse LD50 unreported 75mg/kg (75mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(12), Pg. 35, 1968.
pig LD50 oral 157mg/kg (157mg/kg)   American Journal of Veterinary Research. Vol. 40, Pg. 315, 1979.
pig LD50 oral 157mg/kg (157mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING American Journal of Veterinary Research. Vol. 40, Pg. 315, 1979.
pigeon LD50 oral 23700ug/kg (23.7mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 22010ug/kg (22.01mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Hokkaidoritsu Eisei Kenkyushoho. Report of the Hokkaido Institute of Public Health. Vol. 24, Pg. 35, 1974.
rabbit LD50 oral 10mg/kg (10mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC Bulletin of Experimental Biology and Medicine Vol. 83, Pg. 32, 1977.
rabbit LD50 skin 107mg/kg (107mg/kg)   Bulletin of the Entomological Society of America. Vol. 12, Pg. 117, 1966.
rabbit LD50 unreported 23mg/kg (23mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(12), Pg. 35, 1968.
rat LC50 inhalation 15mg/m3/4H (15mg/m3) BEHAVIORAL: TREMOR

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(12), Pg. 35, 1968.
rat LD50 intraperitoneal 15mg/kg (15mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

BLOOD: OTHER CHANGES
Acta Pharmacologica et Toxicologica, Supplementun. Vol. 49(5), Pg. 67, 1981.
rat LD50 oral 17mg/kg (17mg/kg)   Japan Pesticide Information. Vol. (13), Pg. 36, 1972.
rat LD50 skin 750ug/kg (0.75mg/kg)   Toksikologicheskii Vestnik. Vol. (2), Pg. 35, 1995.
rat LD50 subcutaneous 10800ug/kg (10.8mg/kg)   Acta Physiologica Polonica. Vol. 32, Pg. 507, 1981.
rat LD50 unreported 57mg/kg (57mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(12), Pg. 35, 1968.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
Boiling Point 234.1 deg C   EXP
log P (octanol-water) 1.47 (none)   EXP
Water Solubility 8000 mg/L 20 EXP
Vapor Pressure 0.0158 mm Hg 25 EXP
Henry's Law Constant 5.74E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 9.41E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.