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Substance Name: Butoprozine [INN]
RN: 62228-20-0
UNII: 9XWF3530OG
InChIKey: NRTGWAAGLRTUJZ-UHFFFAOYSA-N

Note

  • Benzoylindolizine derivative related to amiodarone.

Molecular Formula

  • C28-H38-N2-O2

Molecular Weight

  • 434.62
 
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Names and Synonyms

Results Name

  • Butoprozine [INN]

Name of Substance

  • Butoprozine
  • Butoprozine [INN]

Synonyms

  • Butoprozina
  • Butoprozina [INN-Spanish]
  • Butoprozine
  • Butoprozinum
  • Butoprozinum [INN-Latin]
  • UNII-9XWF3530OG

Systematic Name

  • Methanone, (4-(3-(dibutylamino)propoxy)phenyl)(2-ethyl-3-indolizinyl)-

Registry Numbers

CAS Registry Number

  • 62228-20-0

FDA UNII

  • 9XWF3530OG

Related Registry Number

  • 62134-34-3 (hydrochloride)

System Generated Number

  • 0062228200

Structure Descriptors

InChI

1S/C28H38N2O2/c1-4-7-17-29(18-8-5-2)19-11-21-32-26-15-13-24(14-16-26)28(31)27-23(6-3)22-25-12-9-10-20-30(25)27/h9-10,12-16,20,22H,4-8,11,17-19,21H2,1-3H3

InChIKey

NRTGWAAGLRTUJZ-UHFFFAOYSA-N

Smiles

C(=O)(c1c(cc2ccccn12)CC)c1ccc(cc1)OCCCN(CCCC)CCCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 23mg/kg (23mg/kg)   United States Patent Document. Vol. #4957925,
mouse LD50 oral 1600mg/kg (1600mg/kg)   British UK Patent Application. Vol. #2064536,
rat LD50 intravenous 22mg/kg (22mg/kg)   British UK Patent Application. Vol. #2064536,