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Substance Name: Piragliatin [USAN:INN]
RN: 625114-41-2
UNII: BM1HR7IP1L
InChIKey: XEANIURBPHCHMG-SWLSCSKDSA-N

Note

  • Glucokinase activator.

Classification Code

  • Treatment of Type 2 Diabetes

Molecular Formula

  • C19-H20-Cl-N3-O4-S

Molecular Weight

  • 421.903
 
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Names and Synonyms

Name of Substance

  • Piragliatin
  • Piragliatin [USAN:INN]

Synonyms

  • (2R)-2-(3-Chloro-4-(methylsulfonyl)phenyl)-3-((1R)-3-oxocyclopentyl)-N-pyrazinylpropanamide
  • Piragliatin
  • Ro 4389620
  • RO4389620
  • RO4389620-R1440
  • UNII-BM1HR7IP1L

Systematic Name

  • Benzeneacetamide, 3-chloro-4-(methylsulfonyl)-alpha-(((1R)-3-oxocyclopentyl)methyl)-N-pyrazinyl-, (alphaR)-

Registry Numbers

CAS Registry Number

  • 625114-41-2

FDA UNII

  • BM1HR7IP1L

System Generated Number

  • 0625114412

Structure Descriptors

InChI

1S/C19H20ClN3O4S/c1-28(26,27)17-5-3-13(10-16(17)20)15(9-12-2-4-14(24)8-12)19(25)23-18-11-21-6-7-22-18/h3,5-7,10-12,15H,2,4,8-9H2,1H3,(H,22,23,25)/t12-,15+/m0/s1

InChIKey

XEANIURBPHCHMG-SWLSCSKDSA-N

Smiles

c1(c(cc(cc1)[C@@H](C[C@H]1CCC(=O)C1)C(=O)Nc1nccnc1)Cl)S(=O)(=O)C