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Substance Name: Riociguat [USAN:INN:JAN]
RN: 625115-55-1
UNII: RU3FE2Y4XI
InChIKey: WXXSNCNJFUAIDG-UHFFFAOYSA-N

Note

  • Guanylate cyclase stimulator.

Molecular Formula

  • C20-H19-F-N8-O2

Molecular Weight

  • 422.4221
 

Names and Synonyms

Name of Substance

  • Riociguat
  • Riociguat [USAN:INN:JAN]

Synonyms

  • Adempas
  • BAY 63-2521
  • Methyl 4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl(methyl)carbamate
  • Methyl N-(4,6-diamino-2-{1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate
  • Riociguat
  • UNII-RU3FE2Y4XI

Systematic Names

  • Carbamic acid, (4,6-diamino-2-(1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl)methyl-, methyl ester
  • Carbamic acid, N-(4,6-diamino-2-(1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl)-N-methyl-, methyl ester

Registry Numbers

CAS Registry Number

  • 625115-55-1

FDA UNII

  • RU3FE2Y4XI

System Generated Number

  • 0625115551

Structure Descriptors

InChI

1S/C20H19FN8O2/c1-28(20(30)31-2)15-16(22)25-18(26-17(15)23)14-12-7-5-9-24-19(12)29(27-14)10-11-6-3-4-8-13(11)21/h3-9H,10H2,1-2H3,(H4,22,23,25,26)

InChIKey

WXXSNCNJFUAIDG-UHFFFAOYSA-N

Smiles

CN(c1c(nc(nc1N)c2c3cccnc3n(n2)Cc4ccccc4F)N)C(=O)OC