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Substance Name: Turofexorate isopropyl [USAN:INN]
RN: 629664-81-9
UNII: S6KDM312I5
InChIKey: INASOKQDNHHMRE-UHFFFAOYSA-N

Note

  • A synthetic farnesoid X receptor (FXR) agonist that promotes cholesterol lowering in models of dyslipidemia.

Molecular Formula

  • C25-H24-F2 N2-O3

Molecular Weight

  • 438.4716
 

Classification Code

  • Treatment of Lipid Disorders Including Hypertriglyceridemia and Hypercholesterolemia
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Names and Synonyms

Name of Substance

  • Turofexorate isopropyl [USAN:INN]

Synonyms

  • FXR 450
  • FXR-450
  • Turofexorate isopropyl
  • UNII-S6KDM312I5
  • WAY 362450
  • WAY-362450
  • XL 335
  • XL335

Systematic Name

  • Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino(4,5-b)indole-5- carboxylate

Registry Numbers

CAS Registry Number

  • 629664-81-9

FDA UNII

  • S6KDM312I5

System Generated Number

  • 0629664819

Structure Descriptors

InChI

1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3

InChIKey

INASOKQDNHHMRE-UHFFFAOYSA-N

Smiles

CC(C)OC(=O)C1=CN(CC(c2c1[nH]c3c2cccc3)(C)C)C(=O)c4ccc(c(c4)F)F