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Substance Name: Staurosporine
RN: 62996-74-1
UNII: H88EPA0A3N
InChIKey: HKSZLNNOFSGOKW-FYTWVXJKSA-N

Note

  • An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20).

Molecular Formula

  • C28-H26-N4-O3

Molecular Weight

  • 466.5384
 

Classification Code

  • Enzyme Inhibitors
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Names and Synonyms

Name of Substance

  • Staurosporine

MeSH Heading

  • Staurosporine

Synonyms

  • (+)-Staurosporine
  • Alkaloid AM-2282 from Streptomyces
  • AM-2282
  • Antibiotic 230
  • Antibiotic AM 2282
  • CCRIS 3272
  • Staurosporin
  • Staurosporine
  • UNII-H88EPA0A3N

Systematic Names

  • 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
  • 9,13-Epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)-benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S-(9alpha,10beta,11beta,13alpha)-
  • Staurosporine

Registry Numbers

CAS Registry Number

  • 62996-74-1

FDA UNII

  • H88EPA0A3N

Other Registry Number

  • 109189-95-9

System Generated Number

  • 0062996741

Structure Descriptors

InChI

InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1

InChIKey

HKSZLNNOFSGOKW-FYTWVXJKSA-N

Smiles

CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35