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Substance Name: Methionine [USAN:USP:INN:BAN]
RN: 63-68-3
UNII: AE28F7PNPL
InChIKey: FFEARJCKVFRZRR-BYPYZUCNSA-N

Note

  • A sulfur-containing essential L-amino acid that is important in many body functions.

Molecular Formula

  • C5-H11-N-O2-S

Molecular Weight

  • 149.213
 

Classification Codes

  • Amino Acid
  • Mutation Data
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • (L)-Methionine
  • Methionine
  • Methionine [USAN:USP:INN:BAN]

MeSH Heading

  • Methionine

Synonyms

  • (S)-2-Amino-4-(methylthio)butanoic acid
  • 2-Amino-4-(methylthio)butyric acid, (S)-
  • 2-Amino-4-methylthiobutanoic acid (S)-
  • Butanoic acid, 2-amino-4-(methylthio)-, (S)-
  • CCRIS 5528
  • CCRIS 5536
  • Cymethion
  • EINECS 200-562-9
  • h-Met-oh
  • HSDB 4317
  • L(-)-Amino-gamma-methylthiobutyric acid
  • L-(-)-Methionine
  • L-alpha-Amino-gamma-methylmercaptobutyric acid
  • L-alpha-Amino-gamma-methylthiobutyric acid
  • L-gamma-Methylthio-alpha-aminobutyric acid
  • L-Homocysteine, S-methyl-
  • L-Methionine
  • L-Methioninum
  • Liquimeth
  • MET
  • Methilanin
  • Methionine
  • Methionine (VAN)
  • Methioninum
  • Methioninum [INN-Latin]
  • Metionina
  • Metionina [DCIT]
  • Neo-methidin
  • NSC 22946
  • S-Methionine
  • Toxin WAR (Bacillus thuringiensis strain PS205C)
  • UNII-AE28F7PNPL

Systematic Names

  • L-Methionine
  • Methionine
  • Methionine, L-

Superlist Name

  • Methionine, L-

Registry Numbers

CAS Registry Number

  • 63-68-3

FDA UNII

  • AE28F7PNPL

Other Registry Numbers

  • 24425-78-3
  • 7005-18-7

System Generated Number

  • 0000063683

Structure Descriptors

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChIKey

FFEARJCKVFRZRR-BYPYZUCNSA-N

Smiles

C([C@H](CCSC)N)(O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 9500mg/kg (9500mg/kg)   Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
rat LD50 intraperitoneal 4328mg/kg (4328mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Archives of Biochemistry and Biophysics. Vol. 58, Pg. 253, 1955.
rat LD50 oral 36gm/kg (36000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 20, 1983.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 283 dec deg C   EXP
pKa Dissociation Constant 2.28 (none) 25 EXP
log P (octanol-water) -1.87E+00 (none)   EXP
Water Solubility 5.66E+04 mg/L 25 EXP
Vapor Pressure 5.23E-07 mm Hg 25 EST
Henry's Law Constant 2.11E-11 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 5.13E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.