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Substance Name: Sulfanilamide [INN:DCF:NF]
RN: 63-74-1
UNII: 21240MF57M
InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N

Molecular Formula

  • C6-H8-N2-O2-S

Molecular Weight

  • 172.207
 

Classification Codes

  • Agricultural Chemical
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Drug / Therapeutic Agent
  • Germicide, Bactericide, Disinfectant
  • Human Data
  • Mutation Data
  • Natural Product
  • Reproductive Effect
  • Tumor Data

Names and Synonyms

Name of Substance

  • Sulfanilamide
  • Sulfanilamide [INN:DCF:NF]

Synonyms

  • 1162 F
  • 4-14-00-02658 (Beilstein Handbook Reference)
  • 4-Aminobenzenesulfonamide
  • 4-Aminophenylsulfonamide
  • 4-Sulfamoylaniline
  • A-349
  • AI3-00952
  • Albexan
  • Albosal
  • Ambeside
  • Aniline-p-sulfonic amide
  • Antistrept
  • Astreptine
  • Astrocid
  • Avc
  • Bacteramid
  • Bactesid
  • Benzenesulfonamide, 4-amino-
  • Benzenesulfonamide, p-amino-
  • BRN 0511852
  • Caswell No. 809A
  • CCRIS 764
  • Collomide
  • Colsulanyde
  • Copticide
  • Deseptyl
  • Dipron
  • EINECS 200-563-4
  • EPA Pesticide Chemical Code 077902
  • Ergaseptine
  • Erysipan
  • Estreptocida
  • Exoseptoplix
  • F 1162
  • F-1162
  • Fourneau 1162
  • Gerison
  • Gombardol
  • HSDB 223
  • Infepan
  • Lusil
  • Lysococcine
  • Neococcyl
  • NSC 7618
  • Orgaseptine
  • p-Aminobenzenesulfamide
  • p-Aminobenzenesulfonamide
  • p-Aminobenzenesulfonylamide
  • p-Aminophenylsulfonamide
  • p-Anilinesulfonamide
  • p-Sulfamidoaniline
  • p-Sulfamoylaniline
  • PABS
  • Prontalbin
  • Prontosil album
  • Prontosil I
  • Prontosil White
  • Prontylin
  • Pronzin album
  • Proseptal
  • Proseptine
  • Proseptol
  • Pysococcine
  • Rubiazol A
  • Sanamid
  • Septamide album
  • Septanilam
  • Septinal
  • Septolix
  • Septoplex
  • Septoplix
  • Solfanilamide
  • Solfanilamide [DCIT]
  • Stopton album
  • Stramid
  • Strepamide
  • Strepsan
  • Streptagol
  • Streptamid
  • Streptamin
  • Streptasol
  • Streptocid
  • Streptocid album
  • Streptocide (VAN)
  • Streptocide White
  • Streptocidum
  • Streptoclase
  • Streptocom
  • Streptol
  • Strepton
  • Streptopan
  • Streptosil
  • Streptozol
  • Streptozone
  • Streptrocide
  • Sulfamidyl
  • Sulfamine
  • Sulfana
  • Sulfanalone
  • Sulfanidyl
  • Sulfanil
  • Sulfanilamida
  • Sulfanilamida [INN-Spanish]
  • Sulfanilamide
  • Sulfanilamide Vaginal Cream
  • Sulfanilamidum
  • Sulfanilamidum [INN-Latin]
  • Sulfanilimidic acid
  • Sulfocidin
  • Sulfocidine
  • Sulfonamide
  • Sulfonamide P
  • Sulfonylamide
  • Sulphanilamide
  • Sulphonamide
  • Therapol
  • Tolder
  • UNII-21240MF57M
  • White streptocide

Systematic Names

  • Benzenesulfonamide, 4-amino-
  • p-Aminobenzenesulfonamide
  • Sulfanilamide
  • Sulphanilamide

Registry Numbers

CAS Registry Number

  • 63-74-1

FDA UNII

  • 21240MF57M

Other Registry Numbers

  • 102489-34-9
  • 12765-80-9
  • 1337-36-6
  • 1337-39-9
  • 24706-25-0

Related Registry Numbers

  • 10103-15-8 (hydrochloride salt)
  • 6101-31-1 (hydrochloride)

System Generated Number

  • 0000063741

Structure Descriptors

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChIKey

FDDDEECHVMSUSB-UHFFFAOYSA-N

Smiles

S(c1ccc(N)cc1)(N)(=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 2gm/kg (2000mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1079, 1966.
guinea pig LD50 oral 3130mg/kg (3130mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 82, Pg. 86, 1944.
mouse LD50 intraperitoneal 5mg/kg (5mg/kg)   Antibiotics Annual. Vol. 5, Pg. 886, 1957/1958.
mouse LD50 intravenous 500mg/kg (500mg/kg)   Antibiotics Annual. Vol. 5, Pg. 972, 1957/1958.
mouse LD50 oral 3gm/kg (3000mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 48, Pg. 336, 1952.
mouse LD50 subcutaneous 2900mg/kg (2900mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
rabbit LD50 oral 1300mg/kg (1300mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 31(3), Pg. 11, 1966.
rat LD50 intravenous 1400mg/kg (1400mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 211, Pg. 367, 1950.
rat LD50 oral 3900mg/kg (3900mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1072, 1986.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 165.5 deg C   EXP
pKa Dissociation Constant 10.58 (none) 20 EXP
log P (octanol-water) -0.62 (none)   EXP
Water Solubility 7500 mg/L 25 EXP
Vapor Pressure 7.30E-06 mm Hg 25 EST
Henry's Law Constant 1.50E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.30E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.