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Substance Name: Hydroxyprogesterone caproate [USP:INN:JAN]
RN: 630-56-8
UNII: 276F2O42F5
InChIKey: DOMWKUIIPQCAJU-LJHIYBGHSA-N

Note

  • Drugs@FDA Label: Makena is a progestin indicated to reduce the risk of preterm birth in women with a singleton pregnancy who have a history of singleton spontaneous preterm birth. Limitation of use: Makena is not intended for use in women with multiple gestations or other risk factors for preterm birth.

Molecular Formula

  • C27-H40-O4

Molecular Weight

  • 428.609
 

Classification Codes

  • Estradiol Antagonists
  • Estrogen Antagonists
  • Estrogen Receptor Modulators
  • Hormone
  • Hormone Antagonists
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Human Data
  • Progestin
  • Progestins
  • Reproductive Effect
  • Tumor Data
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Names and Synonyms

Name of Substance

  • 17-Alpha-hydroxy-progesterone caproate
  • Hydroxyprogesterone caproate [USP:INN:JAN]

MeSH Heading

  • 17 alpha-Hydroxyprogesterone caproate

Synonyms

  • 17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione
  • 17-alpha-Hexanoyloxypregn-4-ene-3,20-dione
  • 17-alpha-Hydroxy progesterone n-caproate
  • 17-alpha-Hydroxyprogesterone caproate
  • 17-alpha-Hydroxyprogesterone hexanoate
  • 17-Hydroxypregn-4-ene-3,20-dione hexanoate
  • 17-OHPC
  • 17alpha-Caproyloxypregn-4-ene-3,20-dione
  • 17alpha-Hydroxyprogesterone caproate
  • 17alpha-Hydroxyprogesterone n-caproate
  • 17alpha-Hydroxyprogesterone-17alpha caproate
  • 3,20-Dioxo-4-pregnen-17alpha-yl hexanoat
  • 3,20-Dioxopregn-4-en-17alpha-yl caproate
  • Caproate d'hydroxyprogesterone
  • Caproate d'hydroxyprogesterone [INN-French]
  • Caproato de hidroxiprogesterona
  • Caproato de hidroxiprogesterona [INN-Spanish]
  • Corlutin L.A.
  • Delalutin
  • Depo-Proluton
  • Duraluton
  • EINECS 211-138-8
  • Estralutin
  • Gesterol LA 250
  • Gestiva
  • Hormofort
  • HPC
  • HPC (VAN)
  • Hydroxyprogesterone caproate
  • Hydroxyprogesterone hexanoate
  • Hydroxyprogesteroni caproas
  • Hydroxyprogesteroni caproas [INN-Latin]
  • Hylutin
  • Hyproval
  • Hyproval-PA
  • Hyroxon
  • Idrogestene
  • Idroprogesterone caproato
  • Idroprogesterone caproato [DCIT]
  • Kaprogest
  • Lutate
  • Luteocrin
  • Luteocrin depot
  • Lutopron
  • Makena
  • Neolutin
  • Neolutin forte
  • NSC-17592
  • Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)-
  • Primolut depot
  • Proge
  • Progesterone caproate
  • Progesterone retard pharlon
  • Progesterone, 17-hydroxy-, hexanoate
  • Proluton depot
  • Relutin
  • Syngynon
  • Teralutil
  • UNII-276F2O42F5

Systematic Names

  • 17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione
  • Hexanoic acid, ester with 17-hydroxypregn-4-ene-3,20-dione
  • Hydroxyprogesterone caproate
  • Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)-
  • Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate

Superlist Name

  • 17alpha-Hydroxyprogesterone caproate [Progestins]

Mixture Name

  • Deluteval 2X

Registry Numbers

CAS Registry Number

  • 630-56-8

FDA UNII

  • 276F2O42F5

Other Registry Numbers

  • 106111-89-1
  • 2247-38-3
  • 91037-33-1

System Generated Number

  • 0000630568

Structure Descriptors

InChI

InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1

InChIKey

DOMWKUIIPQCAJU-LJHIYBGHSA-N

Smiles

CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(=O)C