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Substance Name: Terazosin hydrochloride anhydrous
RN: 63074-08-8
UNII: 8QOP8Z9955
InChIKey: IWSWDOUXSCRCKW-UHFFFAOYSA-N

Note

  • Induces decreased blood pressure; used in the treatment of benign prostatic hyperplasia.

Molecular Formula

  • C19-H25-N5-O4.Cl-H

Molecular Weight

  • 423.8984
 

Names and Synonyms

Name of Substance

  • Terazosin
  • Terazosin hydrochloride anhydrous

Synonyms

  • Abbott-45975
  • Hytrin
  • Terasin
  • Terazosin HCl
  • Terazosin hydrochloride
  • UNII-8QOP8Z9955
  • Vasocard

Systematic Name

  • Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 63074-08-8

FDA UNII

  • 8QOP8Z9955

Related Registry Number

  • 63590-64-7 (Parent)

System Generated Number

  • 0063074088

Molecular Formulas

Molecular Formula

  • C19-H25-N5-O4.Cl-H

Molecular Formula Fragments

  • C19-H25-N5-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H

InChIKey

IWSWDOUXSCRCKW-UHFFFAOYSA-N

Smiles

COc1cc2c(cc1OC)nc(nc2N)N3CCN(CC3)C(=O)C4CCCO4.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intravenous 277mg/kg (277mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Drug and Chemical Toxicology. Vol. 7, Pg. 435, 1984.