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Substance Name: Glyclopyramide [INN:JAN]
RN: 631-27-6
UNII: KE474IKG1W
InChIKey: HNSCCNJWTJUGNQ-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C11-H14-Cl-N3-O3-S

Molecular Weight

  • 303.7686
 
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Names and Synonyms

Name of Substance

  • Glyclopyramide
  • Glyclopyramide [INN:JAN]

Synonyms

  • 1-((p-Chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)urea
  • 5-20-01-00519 (Beilstein Handbook Reference)
  • BRN 1350984
  • CPBU 7
  • Deamelin S
  • Gliclopiramida
  • Gliclopiramida [INN-Spanish]
  • Glyclopyramide
  • Glyclopyramidum
  • Glyclopyramidum [INN-Latin]
  • UNII-KE474IKG1W

Systematic Names

  • 1-((p-Chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)urea
  • 1-(p-Chlorobenzenesulfonyl)-3-pyrrolidin-1-ylurea
  • Benzenesulfonamide, 4-chloro-N-((1-pyrrolidinylamino)carbonyl)- (9CI)
  • Urea, 1-((p-chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)-

Registry Numbers

CAS Registry Number

  • 631-27-6

FDA UNII

  • KE474IKG1W

System Generated Number

  • 0000631276

Structure Descriptors

InChI

1S/C11H14ClN3O3S/c12-9-3-5-10(6-4-9)19(17,18)14-11(16)13-15-7-1-2-8-15/h3-6H,1-2,7-8H2,(H2,13,14,16)

InChIKey

HNSCCNJWTJUGNQ-UHFFFAOYSA-N

Smiles

c1cc(ccc1S(=O)(=O)NC(=O)NN2CCCC2)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1600mg/kg (1600mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1605, 1977.
mouse LD50 oral 8910mg/kg (8910mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1605, 1977.
mouse LD50 subcutaneous 5500mg/kg (5500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1605, 1977.
rat LD50 intraperitoneal 1620mg/kg (1620mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1605, 1977.
rat LD50 oral 4100mg/kg (4100mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1605, 1977.