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Substance Name: Tetramethylurea
RN: 632-22-4
UNII: 2O1EJ64031
InChIKey: AVQQQNCBBIEMEU-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect

Molecular Formula

  • C5-H12-N2-O

Molecular Weight

  • 116.163
 
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Names and Synonyms

Name of Substance

  • 1,1,3,3-Tetramethylurea
  • Tetramethylurea

Synonyms

  • 1,1,3,3-Tetramethylurea
  • 4-04-00-00225 (Beilstein Handbook Reference)
  • AI3-50988
  • BRN 0773898
  • EINECS 211-173-9
  • HSDB 129
  • N,N,N',N'-Tetramethylurea
  • NSC 91488
  • Temur
  • Tetramethylurea
  • Tetramethyluree
  • Tetramethyluree [French]
  • TMU
  • UNII-2O1EJ64031
  • Urea, 1,1,3,3-tetramethyl-
  • Urea, tetramethyl-

Systematic Names

  • Tetramethylurea
  • Urea, 1,1,3,3-tetramethyl-
  • Urea, N,N,N',N'-tetramethyl-
  • Urea, tetramethyl-

Superlist Name

  • Tetramethylurea

Registry Numbers

CAS Registry Number

  • 632-22-4

FDA UNII

  • 2O1EJ64031

System Generated Number

  • 0000632224

Structure Descriptors

InChI

1S/C5H12N2O/c1-6(2)5(8)7(3)4/h1-4H3

InChIKey

AVQQQNCBBIEMEU-UHFFFAOYSA-N

Smiles

C(N(C)C)(N(C)C)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LDLo intravenous 750mg/kg (750mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 1600, Pg. 333, 1966.
mouse LD50 intravenous 2230mg/kg (2230mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 160, Pg. 333, 1966.
mouse LD50 oral 2920mg/kg (2920mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 160, Pg. 333, 1966.
mouse LDLo intraperitoneal 2900mg/kg (2900mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 188, 1935.
rabbit LD50 skin 3160mg/kg (3160mg/kg) BEHAVIORAL: TREMOR National Technical Information Service. Vol. OTS0559251,
rat LCLo inhalation 312ppm/4H (312ppm) BEHAVIORAL: ATAXIA National Technical Information Service. Vol. OTS0559251,
rat LD50 intravenous 1100mg/kg (1100mg/kg)   Angewandte Chemie, International Edition in English. Vol. 3, Pg. 260, 1964.
rat LD50 oral 794mg/kg (794mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
National Technical Information Service. Vol. OTS0559251,
rat LD50 unreported 1400mg/kg (1400mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1073, 1969.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.20E+00 deg C   EXP
Boiling Point 176.5 deg C   EXP
log P (octanol-water) 0.19 (none)   EXP
Water Solubility 1.00E+06 mg/L 20 EXP
Vapor Pressure 13.9 mm Hg 71 EXP
Henry's Law Constant 8.48E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 4.23E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.