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Substance Name: Foscarnet sodium [USAN:USP:INN:BAN]
RN: 63585-09-1
UNII: 8C5OQ81LWT
InChIKey: DFHAXXVZCFXGOQ-UHFFFAOYSA-K

Classification Codes

  • Antiviral
  • Drug / Therapeutic Agent
  • Human Data

Molecular Formulas

  • C-Na3-O5-P
  • C-O5-P.3Na

Molecular Weight

  • 191.95
 

Names and Synonyms

Name of Substance

  • Foscarnet sodium [USAN:USP:INN:BAN]

Synonyms

  • A 29622
  • Dihydroxyphosphinecarboxylic acid oxide trisodium salt
  • DRG-0017
  • EHB 776
  • Foscarnet sodico
  • Foscarnet sodico [Spanish]
  • Foscarnet sodique
  • Foscarnet sodique [French]
  • Foscarnet sodique [INN-French]
  • Foscarnet sodium
  • Foscarneto sodico
  • Foscarneto sodico [INN-Spanish]
  • Foscarnetum natricum
  • Foscarnetum natricum [INN-Latin]
  • Foscarnetum natricum [Latin]
  • Foscavir
  • Gefin
  • PFA
  • Phosphonoformic acid, trisodium salt
  • Triapten
  • Trisodium carboxyphosphate
  • Trisodium phosphonoformate
  • UNII-8C5OQ81LWT

Systematic Name

  • Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt

Registry Numbers

CAS Registry Number

  • 63585-09-1

FDA UNII

  • 8C5OQ81LWT

Related Registry Number

  • 4428-95-9 (Parent)

System Generated Number

  • 0063585091

Molecular Formulas

Molecular Formulas

  • C-Na3-O5-P
  • C-O5-P.3Na

Molecular Formula Fragments

  • C-O5-P
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3

InChIKey

DFHAXXVZCFXGOQ-UHFFFAOYSA-K

Smiles

C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 384mg/kg (384mg/kg)   United States Patent Document. Vol. #4215113,
women TDLo intravenous 2400mg/kg/6D- (2400mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Lancet. Vol. 2, Pg. 216, 1987.