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Substance Name: Foscarnet sodium [USAN:USP:INN:BAN]
RN: 63585-09-1
UNII: 8C5OQ81LWT
InChIKey: DFHAXXVZCFXGOQ-UHFFFAOYSA-K
Classification Codes
- Antiviral
- Drug / Therapeutic Agent
- Human Data
Molecular Formulas
- C-Na3-O5-P
- C-O5-P.3Na
Molecular Weight
- 191.95
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Names and Synonyms
Name of Substance
- Foscarnet sodium [USAN:USP:INN:BAN]
Synonyms
- A 29622
- Dihydroxyphosphinecarboxylic acid oxide trisodium salt
- DRG-0017
- EHB 776
- Foscarnet sodico
- Foscarnet sodico [Spanish]
- Foscarnet sodique
- Foscarnet sodique [French]
- Foscarnet sodique [INN-French]
- Foscarnet sodium
- Foscarneto sodico
- Foscarneto sodico [INN-Spanish]
- Foscarnetum natricum
- Foscarnetum natricum [INN-Latin]
- Foscarnetum natricum [Latin]
- Foscavir
- Gefin
- NSC 313410
- NSC 758148
- PFA
- Phosphonoformic acid, trisodium salt
- Triapten
- Trisodium carboxyphosphate
- Trisodium phosphonoformate
- UNII-8C5OQ81LWT
Systematic Name
- Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt
Registry Numbers
CAS Registry Number
- 63585-09-1
FDA UNII
- 8C5OQ81LWT
Related Registry Number
- 4428-95-9 (Parent)
System Generated Number
- 0063585091
Molecular Formulas
Molecular Formulas
- C-Na3-O5-P
- C-O5-P.3Na
Molecular Formula Fragments
- C-O5-P
- COMPONENT
- Na
Structure Descriptors
InChI
InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3InChIKey
DFHAXXVZCFXGOQ-UHFFFAOYSA-KSmiles
[Na+].[Na+].[Na+].[O-]C(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 384mg/kg (384mg/kg) | United States Patent Document. Vol. #4215113, | |
women | TDLo | intravenous | 2400mg/kg/6D- (2400mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" | Lancet. Vol. 2, Pg. 216, 1987. |